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N-(2-Kōro-4-waikōpeneri)-N'-sikoroporoporo-urea CAS:796848-79-8
N-Ko te (2-Chloro-4-hydroxyphenyl)-N'-cyclopropyl-urea he matū matū ko tōna tātai ngota C10H11ClN2O2. Nō te akomanga o ngā matū matū urea kua whakakapia ki te rōpū chloro-hydroxyphenyl me te rōpū cyclopropyl. E mōhiotia ana tēnei matū mō tōna uauatanga hanganga me ōna tono pea i roto i ngā rangahau matū me te koiora.
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1,4-Dihydro-7-methoxy-4-oxo-6-quinolinecarboxylic waikawa methyl ester CAS: 205448-65-3
Ko te 1,4-Dihydro-7-methoxy-4-oxo-6-quinolinecarboxylic acid methyl ester he matū matū kei a ia te tātai ngota C12H11NO4. Nō te akomanga quinoline o ngā matū, ā, e tohuhia ana e te rōpū methyl ester e piri ana ki te mowhiti quinoline, me te whakakapinga methoxy kei te tūranga 7 me te rōpū keto kei te tūranga 4.
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AZD-9291 mesylate CAS:1421373-66-1
Ko te AZD-9291 mesylate he matū rongoā me te tātai ngota C28H33N7O4∙CH4O3S. Nō te akomanga o ngā aukati tyrosine kinase, ā, e whakamahia ana i te nuinga o te wā hei rongoā i te mate pukupuku pūkahukahu ehara i te pūtau iti (NSCLC). Ka aro motuhake tēnei rongoā ki ngā momo kua whakarerekētia o te kaiwhakawhiwhi tipu epidermal (EGFR), e kitea nuitia ana i roto i ngā pukupuku NSCLC.
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5-Chloromethyl-2H-1,2,4-triazolin-3-one CAS:252742-72-6
He matū nui te 5-Chloromethyl-2H-1,2,4-triazolin-3-one, he maha ngā whakamahinga i roto i te matū rongoā me te rangahau ahuwhenua. Nō te akomanga o ngā matū triazolinone, e tohuhia ana e te hanganga ngota ahurei e whai wāhi ana ki ana mahi koiora me ngā whakamahinga rongoā pea.
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5-KOROTĪOPENE-2-WARO KŌHORITI CAS:42518-98-9
Ko te 5-Chlorothiophene-2-carbonyl chloride he matū matū nō te akomanga o ngā thienylacyl chlorides. Ko tōna āhua he hanganga ngota kei roto ko te mowhiti thiophene kua whakakapia ki te rōpū chloro i te tūranga-5 me te rōpū carbonyl chloride i te tūranga-2. He mea nui tēnei matū ki te hanga rauropi nā tōna kaha ki te tauhohe me ōna tono pea i roto i ngā rongoā me te pūtaiao rauemi.
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5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone CAS:503615-03-0
Ko te 5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone he matū e mōhiotia ana mō tōna hanganga ngota matatini me ngā tono kanorau i roto i te matū rongoā me te rangahau rongoā. Nō te akomanga pyridinones tēnei matū, ā, he mea motuhake nā tōna whakaritenga ahurei o ngā rōpū mahi, e whakawhiwhi ana i ngā āhuatanga motuhake e tino hira ana mō āna mahi koiora.
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4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester CAS:5909-24-0
Ko te 4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester he matū e mōhiotia ana mō tōna tūranga nui i roto i te matū rongoā me te rangahau rongoā. Kei roto i te kāwai o ngā pyrimidine derivatives tēnei matū, ā, he hanganga ngota motuhake tōna e tino hira ana mō āna mahi koiora me āna tono rongoā.
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3-Kōro-4-Metokipīniramine Waikōroira CAS:41965-95-1
He matū rongonui te 3-Chloro-4-Methoxybenzylamine Hydrochloride e mōhiotia whānuitia ana mō āna whakamahinga i roto i te matū rongoā me te rangahau rongoā. Kei roto tēnei matū i te akomanga o ngā amine kakara, ā, he mea motuhake nā tōna whakaritenga motuhake o ngā rōpū mahi e tino hira ana mō āna mahi koiora.
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3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one CAS:545445-44-1
Ko te 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one he matū rongonui mō tōna hanganga ngota matatini me ngā tono kanorau i roto i te matū rongoā me te whakawhanaketanga rongoā. Nō te akomanga dihydropyridinones tēnei matū, ā, e tohuhia ana e tōna whakaritenga uaua o ngā rōpū mahi, e whakarato ana i ngā āhuatanga motuhake e tika ana mō āna mahi koiora.
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Waikawa L(-)-Thiazolidine-4-carboxylic CAS:34592-47-7
He matū rongonui te waikawa L(-)-Thiazolidine-4-carboxylic e mōhiotia ana mō ōna whakamahinga maha i roto i te matū rongoā me te rangahau rongoā. Nō te akomanga o ngā matū thiazolidine derivatives tēnei matū, ā, he hanganga ngota motuhake tōna e tino hira ana mō ōna mahi koiora me tōna pūmanawa rongoā.
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Nintedanib CAS:656247-17-5
He pūhui kaha te Nintedanib, he pūhui iti te tyrosine kinase (TKI) he mea whakaora nui i roto i ngā mate pukupuku me ngā mate pūtau. Ka puta ōna pānga rongoā mā te aro ki ngā tyrosine kinase maha e uru ana ki te angiogenesis, te fibrogenesis, me te whakahaere i te tipu o te pukupuku.
