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5-Bromo-2-chloro-4-(cyclopentylamino)pyrimidine CAS:733039-20-8
5-He matū te Bromo-2-chloro-4-(cyclopentylamino)pyrimidine e rangahauhia ana i roto i ngā rangahau rongoā. He hanganga pyrimidine tōna me ngā whakakapinga bromo me te chloro, he mea nui pea mō ngā tono rongoā, e aro ana ki ngā tikanga mate motuhake, ki ngā ara koiora rānei i roto i te kimi rongoā.
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![4-[6-[[6-(1-Butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino]pyridin-3-yl]piperazine-1-waikawa carboxylic tert-butyl ester CAS:866084-31-3](https://cdn.globalso.com/xindaobiotech/2WI17RKBWR11PZUDNLH66.png)
4-[6-[[6-(1-Butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino]pyridin-3-yl]piperazine-1-waikawa carboxylic tert-butyl ester CAS:866084-31-3
4-Ko te [6-[[6-(1-Butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester he matū matatini kei roto he pūtake piperazine me ngā rōpū mahi tae atu ki te pyridine, pyrimidine, me te tert-butyl ester. Ka tautokohia e tōna hanganga ngā tono pea i roto i te matū rongoā me te whanaketanga rongoā nā te mea he maha ngā momo pharmacophores.
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Bortezomib CAS:179324-69-7
Ko te Bortezomib he matū rongoā e whakamahia ana hei rongoā i te myeloma maha me te lymphoma pūtau mantle. Nō te akomanga o ngā aukati proteasome, e aro ana ki ngā whākōkī proteolytic i roto i ngā pūtau hei whakararuraru i tā rātou mahi me te whakaoho i te apoptosis (mate pūtau kua whakaritea). Mā tēnei tikanga ka whai hua ki ētahi mate pukupuku e puta ai te tipu pūtau kāore i te whakahaeretia.
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Metila 2-bromomethyl-3-nitrobenzoate CAS:98475-07-1
He matū te Methyl 2-bromomethyl-3-nitrobenzoate, kei reira te rōpū nitro i te tūranga-3 me te rōpū bromomethyl i te tūranga-2 o te tuarā benzoate. E whakamahia ana i roto i te hanga rauropi hei takawaenga maha-whakamahinga, e āhei ai te hanganga o ngā ngota matatini me ngā rōpū mahi motuhake.
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Pemetrexed disodium INT-5 CAS:165049-28-5
Ko te Pemetrexed disodium INT-5 he rongoā oncology kua whakarōpūtia i raro i ngā kaihoko chemotherapy antifolate. E whakamahia ana i te nuinga o te wā hei rongoā i ngā momo mate pukupuku, tae atu ki te mesothelioma, te mate pukupuku pūkahukahu kore-pūtau iti, me ngā mate pukupuku metastatic motuhake.
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Pemetrexed disodium INT-4 CAS:137281-39-1
Ko te Pemetrexed disodium INT-4 he rongoā chemotherapy antifolate e whakamahia ana i roto i te oncology. E whakamahia ana hei rongoā i ngā momo mate pukupuku, tae atu ki te mesothelioma, te mate pukupuku pūkahukahu kore-pūtau iti, me ngā mate pukupuku metastatic motuhake.
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Pemetrexed disodium INT-3 CAS:155405-80-4
Ko te Pemetrexed disodium INT-3 he rongoā chemotherapy antifolate e whakamahia ana i roto i te oncology. E whakamahia ana hei rongoā i ngā momo mate pukupuku, tae atu ki te mesothelioma, te mate pukupuku pūkahukahu kore-pūtau iti, me ngā mate pukupuku metastatic motuhake.
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Pūtake Terbinafine CAS:91161-71-6
He matū rongoā hohe te turanga Terbinafine e whakamahia ana hei rongoā i ngā mate harore. Nō te akomanga allylamine o ngā rongoā harore, ā, e mōhiotia ana mō tōna whai huatanga ki ngā dermatophytes, ngā rewena, me ngā pokepokea ai.
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2-Kōro-4,6-dimethoxy-1,3,5-triazine CAS:3140-73-6
2-He matū te Chloro-4,6-dimethoxy-1,3,5-triazine e whakamahia ana hei poraka hanga maha i roto i ngā tukanga hanga matū me te whakarerekētanga matū. Kei roto ko ngā rōpū mahi chloro me te methoxy e piri ana ki te hanganga mowhiti triazine, e āhei ai te whakamahi i roto i ngā tauhohenga matū me ngā hanganga matū.
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2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile CAS:950596-58-4
2-Ko te Amino-4,5-bis(2-methoxyethoxy)benzonitrile he matū e whakamahia ana i roto i te rangahau rongoā, e tohuhia ana e te hanganga benzonitrile me ngā whakakapinga amino me te methoxyethoxy, he mea nui pea mō ngā tono rongoā motuhake.
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(1R)-(S)-pinanediol-1-Ammonium Trifluoroacetate-3-methlbutane-1-boronate CAS:179324-87-9
Ko te (1R)-(S)-Pinanediol-1-Ammonium Trifluoroacetate-3-Methylbutane-1-Boronate he matū e tohuhia ana e te hanganga matatini e whakaatu ana i te tuara pinanediol, he rōpū ammonium trifluoroacetate, me te mahi boronate ester. Ka whakamahia i roto i te hanga rauropi hei poraka hanga chiral, e āhei ai te hanga i ngā matū stereospecific me ngā takawaenga rongoā.
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Diethyl L-glutamate hydrochloride CAS:1118-89-4
Ko te Diethyl L-glutamate hydrochloride he matū e whakamahia ana hei takawaenga hangai i roto i te rangahau rongoā me te hanga rauropi. I ahu mai i te waikawa L-glutamic, ā, he matū mua i roto i te hanga o ngā momo rongoā me ngā matū hohe koiora.
