Letrozole CAS:112809-51-5 Kaihanga Kaiwhakarato

Ko Letrozole tētahi wāhanga o tētahi whakatupuranga hou o ngā aukati aromatase tino whiriwhiri, ā, he benzotriazole derivative i hangaia ā-hangai. Ka ārai a Letrozole i te aromatase kia whakaitihia ngā taumata estrogen, ā, ka ārai i te estrogen ki te whakaoho i te tipu o te pukupuku. Ko tōna kaha in vivo he 150-250 ngā wā kaha ake i te aukati aromatase o te whakatupuranga tuatahi a Amarante. Nā te mea he tino whiriwhiri, kāore e pā ki ngā mahi glucocorticoid, mineralocorticoid me te tairoi; ahakoa i roto i ngā horopeta teitei, kāore he pānga aukati ki te tukunga corticosteroid adrenal, ka hoatu he taupū maimoatanga teitei.

Tonohia, Tonoa rānei he Tāpaetanga

Taipitopito Hua

Ngā Tohu Hua

Te Whakamahinga me te Pānga

Ka taea te hanga i te Letrazole i roto i ngā taahiraa e rua mai i te 4-bromomethyl-benzonitrile me te 1,2,4-triazole, ā, he tuatoru o ngā whakatupuranga o te aukati aromatase. He aukati tino motuhake o te P450arom e aukati ana i te hurihanga o te androstenedione ki te estrone. I tere tonu te whakahekenga o te estrogen plasma, ā, he roa te wā. Ka tutuki tēnei me te kore e aukati i te hangahanga o ētahi atu steroid, koia te aukati aromatase tino whiriwhiri kua whakamatautauria. He mahi anti-pukupuku whakamiharo a Letrazole, he pai te manawanui, ā, kāore he pānga taha paitini. He 10,000 ngā wā he kaha ake i te aminoglutethimide, in vivo, te aukati aromatase tuatahi kua whakapumautia.

Tauira Hua

Te Tākai Hua:

Ngā Mōhiotanga Tāpiri:

Te hanganga	C17H11N5
Whakamātautau	99%
Āhua	Paura mā
Nama CAS	112809-51-5
Te tākai	25KG
Te Ora o te Wāhi	2 tau
Rokiroki	Penapena ki te wāhi hauhautanga, maroke hoki
Tiwhikete	ISO.