L-Lactate dehydrogenase CAS:9001-60-9

Ko te pānga o te L-Lactate dehydrogenase (LDH) ko tōna tūranga i roto i te pākia o te pūngao pūtau me tōna whai wāhi ki te hurihanga o te pyruvate ki te lactate. Ka āwhina te LDH ki te pupuri i te taurite pūngao i roto i ngā pūtau mā te whakahaere i te hurihanga o te pyruvate, he hua taha o te pākia o te hukahuka, ki te lactate. Ka puta tēnei tukanga, e mōhiotia ana ko te glycolysis anaerobic, ina iti te tuku hāora.

He mahi nui anō tā te LDH ki te hangarua i te lactate. I te wā e kaha ana te whakakori tinana, i te wā rānei e iti ana te hāora, ka taea e te lactate te kohikohi i roto i ngā kiko. Ka āwhina te LDH ki te hangarua i te lactate mā te huri anō ki te pyruvate, ka taea te whakamahi hei tūāpapa mō te whakaputa pūngao, te huri rānei ki te glucose mā te gluconeogenesis. Mā tēnei tikanga hangarua lactate ka taea e ngā pūtau te whakamahi pai i te lactate hei pūtake pūngao, ā, ka āwhina hoki ki te aukati i te kohikohinga o te lactate, ka kino pea ki te mahi a te pūtau.

He maha ngā whakamahinga o te LDH i roto i te ao hauora. Ko tētahi o ōna whakamahinga nui he tohu tātaritanga mō ētahi mate. Ko te nui haere o te LDH i roto i te toto ka tohu pea i te kino o te kiko, i te aroaro rānei o ngā mate pēnei i te kino o te ate, te mate ngakau, me ētahi momo mate pukupuku. He maha ngā wā ka aroturukitia ngā taumata LDH i roto i ngā tautuhinga haumanu hei aromatawai i te haere whakamua o te mate me te urupare ki te maimoatanga.