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Phosphate Fludarabine CAS:75607-67-9
Ko te Fludarabine phosphate he rite ki te adenosine, e whakamahia ana i te nuinga o te wā hei rongoā i ngā mate pukupuku toto pērā i te mate pukupuku toto mau tonu (CLL) me te lymphoma kore-Hodgkin. Ka mahi mā te whakararuraru i te hanganga me te whakatikatika o te DNA, ā, ka mutu ka puta te apoptosis i roto i ngā pūtau matepukupuku tere te wehewehe. Mēnā ka tukuna mā te uaua, mā te waha rānei, ka whakaatuhia e te fludarabine phosphate ngā āhuatanga ārai mate, ka whai hua i roto i ētahi āhuatanga engari me aroturukihia hoki ngā pānga kino. Ko tōna whakaurunga he whanaketanga nui i roto i te chemotherapy, e whakarato ana i tētahi huarahi kua arotahihia kua whakapai ake i ngā putanga mō te maha o ngā tūroro he matepukupuku toto motuhake.
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Waikawa o-Toluic CAS:118-90-1
Ko te waikawa o-Toluic, e mōhiotia ana ko te waikawa ortho-toluic, he waikawa carboxylic kakara me te tātai ngota C₈H₈O₂. Kei roto he rōpū methyl me te rōpū waikawa carboxylic e piri ana ki ngā ngota waro tata i runga i te mowhiti benzene, e whakarato ana i ngā āhuatanga matū motuhake me te tauhohenga. Kei te noho tēnei matū hei totoka kore tae, ā, ka wairewa i roto i ngā whakarewa waro. He takawaenga nui te waikawa o-Toluic i roto i te hanganga o ngā momo matū, tae atu ki ngā tae, ngā rongoā, me ngā matū ahuwhenua. Mā tōna hanganga ahurei me ngā rōpū mahi ka āwhina i ngā tauhohenga maha, ka whai hua i roto i ngā tautuhinga ahumahi me ngā tautuhinga taiwhanga.
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Te waikawa waikawa glycinonitrile CAS: 6011-14-9
Ko te glycinonitrile hydrochloride he matū matū kei roto ko te tātai ngota C₂H₄ClN₃, he mea hanga mai i tētahi matū glycine e whakauru ana i tētahi rōpū mahi nitrile. E mōhiotia ana tēnei totoka tioata mā mō ōna tono pea i roto i te hanganga rauropi me te matū rongoā. Ka taea e te glycinonitrile te mahi hei poraka hanga maha i roto i te hanganga o ngā momo ngota koiora hohe, tae atu ki ngā rongoā me ngā matū ahuwhenua. Nā ōna āhuatanga ahurei ka waiho hei kaitono whakamīharo mō ētahi atu rangahau me te whanaketanga, inā koa i roto i te hoahoa o ngā matū me ngā mahi rongoā motuhake.
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Warowaihā Vinylene CAS:872-36-6
Ko te vinylene carbonate (VC) he matū carbonate hurihuri me te tātai ngota C₃H₄O₃. Ko tōna āhuatanga ko tōna rōpū vinyl me te rōpū mahi carbonyl, e hanga ana hei monomer tino tauhohe i roto i te matū waro. Ko te VC te nuinga o te wā e whakamahia ana hei tāpiri electrolyte i roto i ngā pākahiko lithium-ion, e whakarei ake ana i te hanganga o te interphase electrolyte totoka pumau (SEI), e whakapai ake ana i te mahi pākahiko me te roa o te ora. Hei tāpiri, ko te vinylene carbonate te poraka hanga mō ngā momo polymerization me te hanga matū, e whakaatu ana i tōna hiranga i roto i te pūtaiao rauemi me te hanga waro.
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Disodium 5′-Guanylate CAS: 5550-12-9
Ko te Disodium 5′-guanylate, e mōhiotia whānuitia ana ko te GMP, he matū ira-nucleotide e whai wāhi nui ana ki ngā tukanga matū koiora i roto i ngā rauropi ora. Hei tāpiri kai me te whakarei ake i te reka, ka whakamahia pinepinetia me te monosodium glutamate (MSG) hei whakarei ake i te reka umami i roto i ngā mahi tunu kai. Ka mahi te GMP hei ngota tohu e uru ana ki te whakawhitiwhiti kōrero pūtau me te whakahaere i te pākia o te tinana, e awe ana i ngā tukanga pēnei i te hanga pūmua me te pākia o te pūngao. Hei tāpiri, ka whakamahia i roto i te rangahau koiora ngota hei matū me te whakahohe mō ngā tauhohenga whākōkī, e whakaatu ana i tōna hiranga i tua atu i tōna tūranga ki te whakarei ake i te reka.
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waikawa p-Toluic CAS:99-94-5
Ko te waikawa p-Toluic, e mōhiotia ana ko te waikawa para-toluic, he waikawa carboxylic kakara me te tātai ngota C₈H₈O₂. Kei roto i tēnei he matū toluene kei reira te rōpū carboxyl (-COOH) me te rōpū methyl (-CH₃) kei ngā taha rerekē o te mowhiti benzene. Mā tēnei whakaritenga hanganga ka puta ngā āhuatanga matū motuhake me te kaha tauhohenga. Ka puta te waikawa p-Toluic hei totoka tioata ma, ā, ka wairewa i roto i ngā whakarewa waro. He takawaenga nui i roto i te hanganga o ngā momo matū, tae atu ki ngā tae, ngā rongoā, me ngā matū ahuwhenua, e whakaatu ana i tōna whānui me tōna hiranga i roto i ngā tono ahumahi me ngā tono taiwhanga.
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N,N'-Diaminoguanidine monohydrochloride CAS:36062-19-8
Ko te N,N'-Diaminoguanidine monohydrochloride (DGH) he matū waro kei roto ko te tātai C₂H₈ClN₄, he mea hanga mai i tētahi guanidine derivative e rua ngā rōpū amine. Ko tēnei matū maha-whakamahinga e whakamahia ana i roto i ngā tono rongoā, inā koa hei matū mua i roto i te hanganga o ngā momo ngota koiora me ngā rongoā. Kua arohia te DGH mō ōna āhuatanga rongoā pea, tae atu ki te whakamahinga i roto i te rongoā i ētahi mate hauora pēnei i te mate huka me ngā mate manawa. Nā tōna hanganga ahurei ka taea e ia te whai wāhi ki ngā tauhohenga matū koiora nui, e whakaatu ana i tōna hiranga i roto i te matū rongoā me te whanaketanga rongoā.
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Capecitabine CAS:154361-50-9
Ko te Capecitabine he rongoā chemotherapy ā-waha e whakamahia ana hei rongoā i ngā momo mate pukupuku, tae atu ki ngā mate pukupuku colorectal me ngā mate pukupuku ū. He rongoā tāpiri tēnei ka hurihia hei momo hohe, 5-fluorouracil (5-FU), i roto i te tinana, ka puta ōna pānga ārai mate pukupuku mā te aukati i te hanganga DNA me te whakararuraru i te mahi RNA i roto i ngā pūtau tere wehewehe. He maha ngā wā ka whakamahia te Capecitabine me ētahi atu kaihoko chemotherapy hei whakarei ake i te whai huatanga. Ko tana whakahaerenga ā-waha he huarahi pai hei whakakapi i ngā maimoatanga uaua, hei whakapai ake i te piripono o te tūroro. Ahakoa e pai ana te manawanui ki te nuinga o te wā, ka taea e te capecitabine te whakaputa i ngā pānga taha pēnei i te mate ringa-waewae, te whakapairuaki, me te myelosuppression.
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4(1H)-Pyrimidinone,5-fluoro-2-methoxy-,hydrazone CAS:166524-64-7
Ko te 4(1H)-Pyrimidinone, 5-fluoro-2-methoxy-, hydrazone he matū waro motuhake e tohuhia ana e te aroaro o te mowhiti pyrimidinone me te mahi hydrazone. Me te tātai ngota C₉H₁₀FN₃O₂, kei roto i tēnei matū he ngota fluorine me te rōpū methoxy e whai wāhi ana ki ōna āhuatanga matū ahurei. E mōhiotia ana ngā hydrazone mō ō rātou tauhohenga me te whai huatanga i roto i ngā tono hanga waro. Nā tōna hanganga, he pānga pea tēnei matū ki te matū rongoā, inā koa hei mua, hei takawaenga rānei i roto i te whanaketanga o ngā ngota bioactive me te hiranga rongoā.
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Waikawa 3-Methylsalicylic CAS:83-40-9
Ko te waikawa 3-Methylsalicylic, e mōhiotia ana ko te waikawa 3-(methyl)salicylic, ko te waikawa 3-methyl-2-hydroxybenzoic rānei, he matū kakara me te tātai ngota C₈H₈O₃. Kei roto ko te rōpū hydroxyl (-OH) me te rōpū waikawa carboxylic (-COOH) e piri ana ki te mowhiti benzene, me te rōpū methyl e whakanoho ana ki te rōpū hydroxyl. Mā tēnei whakaritenga hanganga ka puta he āhuatanga matū ahurei e whai hua ai i roto i ngā tono maha. Ka whakamahia te waikawa 3-Methylsalicylic i roto i te hanga rauropi, ngā rongoā, me te mea he poraka hanga mō ētahi atu matū. Ko ōna mahi koiora pea e whakaatu ana i tōna hiranga i roto i te matū rongoā me te rangahau.
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(+)-5-Iodo-2′-deoxyuridine CAS:54-42-2
Ko te (+)-5-Iodo-2′-deoxyuridine (IUdR) he rite ki te nucleoside hangai o te deoxyuridine, e whakauru ana i te ngota iodine i te tūranga-5 o te mowhiti uracil. Hei kaihoko ārai huaketo me te mate pukupuku, kua rangahaua te IUdR mō tōna kaha ki te aukati i te hanganga DNA i roto i ngā pūtau tere wehewehe, ā, he tino whai hua ki te rangahau mate pukupuku me ngā rautaki maimoatanga. Ka mahi mā te whakararuraru i te tukanga tāruarua noa o te DNA, ka arahi ki te mate pūtau i roto i ngā kiko neoplastic. Hei tāpiri, ka whakamahia te IUdR i roto i ngā momo maimoatanga whakamātautau, tae atu ki te brachytherapy mō ngā mate pukupuku ā-rohe, nā tōna whai huatanga ki te arotahi ki ngā pūtau pukupuku.
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![2-Azabicyclo[2.2.1]hept-5-en-3-one CAS:49805-30-3](https://cdn.globalso.com/xindaobiotech/VYH6FUCIIBE_I7B6OOPY333.png)
2-Azabicyclo[2.2.1]hept-5-en-3-one CAS:49805-30-3
Ko te 2-Azabicyclo[2.2.1]hept-5-en-3-one he matū waro bicyclic e tohuhia ana e te ngota hauota i roto i tōna hanganga mowhiti me te rōpū mahi ketone. Me te tātai ngota C₇H₉NO, nō tētahi akomanga o ngā matū azabicyclic tēnei matū kua kukume i te aro ki te hanganga waro me te matū rongoā. Nā tōna hanganga ahurei ka whakawhiwhia he āhuatanga matū whakamere, ka waiho hei takawaenga whai hua i roto i te hanganga o ngā momo ngota koiora. Ko te rangahau mō ōna tono pea e kapi ana i ngā rongoā me ngā matū ahuwhenua, hei tūāpapa mō te whakawhanake i ngā matū he hiranga rongoā.
