1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carbonitrile CAS:2158267-70-8

He mahi nui tā te 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carbonitrile hei takawaenga i roto i te hanganga o ngā matū matatini, koiora-kaha me ngā tono rongoā pea. Mā tōna whakaurunga ki roto i ngā anga ngota ka taea e ngā kairangahau te tūhura i ngā rongoā hou e aro ana ki ngā momo rongoā rerekē pēnei i ngā aukati kinase, ngā whakamātautau fluorescent, ngā tono matū rauemi rānei. Ko te noho mai o te matua pyrazole me te rōpū dioxaborolane ka whakauru i te tauhohenga motuhake me ngā āhuatanga rongoā, ka whai hua mō te rangahau matū rongoā. I roto i ngā mahi kimi rongoā, ka taea e tēnei matū te mahi hei tīmatanga mō te hoahoa i ngā rongoā pea, me te whakamahi i ōna āhuatanga hanganga hei whakarerekē i te mahi koiora me ngā āhuatanga pharmacokinetic. Hei tāpiri, ka tukuna e te rōpū mahi dioxaborolane ngā whai wāhitanga mō te whakaputanga me te matū honohono-whakawhiti, ka arahi pea ki te whanaketanga o ngā ngota hou me ngā āhuatanga koiora whakarei ake me ngā kōtaha pharmacokinetic kua whakapai ake. Hei tāpiri atu ki tēnā, i roto i ngā taiao mātauranga me ngā taiao ahumahi, ka taea e ngā kairangahau te whakamahi i tēnei poraka hanga hei whakarite i ngā whare pukapuka o ngā momo pānga rerekē mō ngā rangahau whanaungatanga hanganga-mahi, hei āwhina i te tautuhi i ngā matū mata me ngā pānga koiora e hiahiatia ana. Ko tana mahi i roto i te hanganga matū ka toro atu ki te hanga i ngā takawaenga rongoā me te whakawhanaketanga o ngā tikanga hanga hou, e whakaatu ana i tōna whai huatanga whānui puta noa i ngā kaupapa pūtaiao. I te nuinga, he mahi nui te 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carbonitrile i roto i te whai i te kitenga rongoā auaha me te rangahau matū, e whakarato ana i tētahi tūāpapa mō te whakawhanaketanga o ngā ngota ngota koiora kaha me ngā takawaenga rongoā.