β-Nicotinamide Adenine Dinucleotide CAS:53-84-9

He mea nui te NAD+ ki te mahi pūtau, ā, kua nui ake te hiahia ki ngā mara pēnei i te rangahau koroheketanga, te pākia o te pūtau, me te hauora o te pūtau. Hei coenzyme, ka uru te NAD+ ki ngā tauhohenga redox e tika ana mō te whakaputa pūngao i roto i te mitochondria, e tautoko ana i ngā tukanga pēnei i te glycolysis, te huringa waikawa tricarboxylic, me te phosphorylation oxidative. Hei tāpiri, ko te NAD+ te tūāpapa mō ngā whākōkī pēnei i te sirtuins me te PARPs, e whai wāhi ana ki te whakatikatika DNA, te whakahaere i te whakaaturanga ira, me ngā ara urupare ahotea pūtau. I ngā tau tata nei, kua nui ake te aro ki ngā precursors NAD+, pēnei i te nicotinamide riboside (NR) me te nicotinamide mononucleotide (NMN), hei tāpiringa pea hei tautoko i ngā taumata NAD+ i roto i ngā pūtau. E kī ana ngā rangahau ko te pupuri i ngā taumata NAD+ tino pai ka whai wāhi pea ki te biogenesis mitochondrial, te homeostasis metabolic, me te roa o te ora. Nō reira, kei te tirotirohia ngā precursors NAD+ mō tō rātou kaha ki te whakaiti i te hekenga e pā ana ki te koroheketanga, te tautoko i te koroheketanga hauora, me te aro ki ngā taurite kore pākia e pā ana ki ngā āhuatanga pēnei i te momona me te mate huka. Hei tāpiri, ko te NAD+ tētahi wāhanga e piki haere ana te hiahia ki ngā hākinakina me te physiology whakakori tinana nā tōna whai wāhi ki te pākia o te pūngao me te mahi mitochondrial. Kei te haere tonu ngā rangahau e tūhura ana i te whakarerekētanga NAD+ e pā ana ki te mahi whakakori tinana, te whakaora uaua, me te kaha manawanui, me ngā pānga pea ki te mahi hākinakina me te manawanui tinana. I te nuinga, ko te NAD+ me ōna mua he wāhanga rangahau pūtaiao hohe me ngā tono pea e pā ana ki te koroheketanga, te hauora pūtau, te pākia o te tinana, me te mahi whakakori tinana, e tohu ana i te whenua whānui me te whanaketanga o te rangahau me te hiranga rongoā pea.