Z-MeVal-OH CAS:42417-65-2

He whānuitia te whakamahinga o tēnei hua e ngā kairangahau me ngā kamupene rongoā mō te hanga peptide kei roto ngā toenga N-methylvaline. E mōhiotia ana te N-methylvaline mō tōna kaha ki te whakarei ake i te pumau o te āhua me te urunga o te kiriuhi o ngā peptide, ka waiho hei poraka hanga nui i roto i te whanaketanga o ngā rongoā me ngā rongoā e hangai ana ki te peptide. He tino parakore te Z-MeVal-OH, ā, he hototahi ki ētahi atu matū, ka waiho hei whiringa pono mō ngā kaupapa hanga peptide. He taputapu maha ngā mahi a te Z-MeVal-OH mō ngā kairangahau i roto i ngā mara o te matū koiora, te rongoā, me te kimi rongoā. Nā tōna pumau, te parakore, me te hototahitanga ka waiho hei wāhanga nui i roto i te hanga o ngā peptide kei roto te N-methylvaline, he tono pea ki te whanaketanga rongoā, te rangahau koiora, me ngā wawaotanga rongoā. Mā te whakauru i te Z-MeVal-OH ki roto i ngā raupapa peptide, ka taea e ngā kairangahau te hanga i ngā pūhui hou me te pai ake o te mahi koiora me ngā āhuatanga pharmacokinetic, ka whakatairanga i te mara o te kimi rongoā e hangai ana ki te peptide.