TOPS CAS:40567-80-4 Utu Kaihanga

He pānga motuhake tō te konutai 3-(N-ethyl-3-methylanilino)propanesulfonate, e mōhiotia ana ko MESNa, me tōna whakamahinga i roto i te matū koiora me te koiora ngota. Ko te nuinga o te wā ka whakamahia hei kaiwhakaiti mō te tiaki i ngā rōpū thiol (-SH) i roto i ngā pūmua me ngā peptide.

He kaha te mahi a te MESNa hei kaiwhakaiti, ka taea te huri i ngā here disulfide (-SS-) i roto i ngā pūmua ki ngā rōpū sulfhydryl (-SH). He mea nui tēnei tukanga whakaiti i roto i ngā tono pūtaiao maha, tae atu ki te tātari pūmua, te purenga, me te hangarau pūmua.

Ko ētahi o ngā whakamahinga motuhake o te MESNa ko:

Te Whakakorenga i te Pūmua: Ka taea te whakamahi i te MESNa hei whakakore i te āhua o ngā pūmua mā te wawahi i ngā here disulfide, ā, mā reira ka hurahia te hanganga pūmua me te whakahaere i ētahi atu tātaritanga, i te purenga rānei o te pūmua.

Te Whakaiti i te Whakakotahitanga Pūmua: Ka taea e te MESNa te aukati i te whakakotahitanga pūmua mā te whakaiti i ngā here disulfide, kia mau ai te pumau me te wairewatanga o te pūmua i roto i te wairewa.

Te Tapanga Pūmua: Ka taea te whakamahi i te MESNa hei whakauru i ngā tapanga, i ngā whakarerekētanga rānei ki ngā toenga cysteine ​​motuhake i roto i ngā pūmua mā te wawahi i ngā here disulfide me te whakaatu i ngā rōpū sulfhydryl (-SH).

Te Whakapūtanga Anō o te Pūmua: Ka whakamahia te MESNa hei āwhina i te whakapūtanga anō o te pūmua i muri i te whakakorenga mā te whakaiti i ngā here disulfide me te āwhina i te hanganga tika o ngā hanganga pūmua.