Konutai Alpha-Ketoisocaproate CAS:4502-00-5 Kaihanga Kaiwhakarato

Ko te Sodium Alpha-Ketoisocaproate he matūriki leucine e mōhiotia ana ka whakaoho i te whakaputanga insulin mai i ngā pūtau β o te pancreas. E kitea ana ka whakapai ake te werohanga o te aα-Ketoisocaproate i roto i te toto, i te āhua endotoxemic. Ko ngā tinana ketone e puta mai ana i tōna huringa, ka taea te whakamahi hei puna pūngao. Ko te kohikohinga o te waikawa α-Ketoisocaproic ka tohuhia i roto i te ketoaciduria mekameka peka, e puta mai ana i te korenga o te mahi dehydrogenase waikawa L-2-keto mekameka peka. Ka puta te wehenga o te waikawa α-Ketoisocaproic i roto i te tauhohenga phosphorylation oxidative, ā, ka mahi hei aukati metabolic o te α-ketoglutarate dehydrogenase. Nō reira, ka puta he hapa i roto i te homeostasis mitochondrial, e kitea ana i roto i te ketoaciduria mekameka peka.