Sodium Alpha-Ketoisocaproate CAS:4502-00-5 Kaihanga Kaihanga

Ko te Sodium Alpha-Ketoisocaproate he metabolite leucine e mohiotia ana hei whakakorikori i te hunanga o te insulin mai i nga pūtau β o te pancreas.Ka kitea te whaowhia o te aα-Ketoisocaproate ki te whakapai, te ahua endotoxemic.Ko nga tinana ketone ka puta mai i tana huringa, ka noho hei puna kaha.Ko te kohikohinga o te waikawa α-Ketoisocaproic e tohuhia ana i roto i te ketoaciduria mekameka manga, i puta mai na te kore o te mekameka L-2-keto acid dehydrogenase mahi.Ko te waikawa α-Ketoisocaproic ka wehewehe i roto i te tauhohenga phosphorylation oxidative me te mahi hei aukati metabolic o te α-ketoglutarate dehydrogenase.Na, ka arahi ki te koha o te mitochondrial homeostasis, ka kitea i roto i te ketoaciduria mekameka manga.