Simvastatin CAS:79902-63-9 Kaihanga Kaiwhakarato

He āhua hanga-haurua te Simvastatin, he āhua wai-whakahē ake, he rite ki te lovastatin. Pērā i te lovastatin, he aukati motuhake te simvastatin i te HMG-CoA reductase, ā, e whakamahia ana hei rongoā hei whakaiti i te cholesterol LDL. Nō nā tata nei, kua noho ngā statin hei whakamātautau matū koiora nui i roto i te koiora pūtau. Ka taea te hono atu ki tā rātou whai wāhi ki ngā kaupapa maha ki tā rātou momo mahi matua, heoi, kāore i te tino kitea te tikanga mahi o ētahi atu pānga. He aukati motuhake te Simvastatin i te HMG-CoA reductase, te whākōkī e whakaoho ana i te hurihanga o te HMG-CoA ki te mevalonate, he taahiraa tōmua i roto i te biosynthesis cholesterol. E whakamahia ana hei rongoā mō te hypercholesterolemia, nā te mea ka whakaitihia ngā taumata o ngā lipoproteins iti-kiato me ngā triglycerides, ā, ka whakapiki ake i ngā taumata lipoprotein teitei-kiato.