S)-(+)-Camptothecin CAS:7689-03-4

He pūmanawa te (S) -(+)-Camptothecin mō te rongoā i ngā momo mate pukupuku, inā koa i roto i te ao o te chemotherapy. Ko tana tikanga mahi ko te aro me te aukati i te mahi a te topoisomerase I, he whākōkī nui mō te wetewete i te DNA i te wā o te wehenga pūtau. Mā te whakakore i tēnei tukanga, ka ārai te (S)-(+)-Camptothecin i ngā pūtau mate pukupuku mai i te whakaputa uri me te horapa, ā, ka mutu ka puta te apoptosis, te mate pūtau kua whakaritea rānei. Kua whakaatuhia e tēnei matū he whai huatanga ki ētahi momo mate pukupuku, tae atu ki te mate pukupuku colorectal, te mate pukupuku ovarian, me te mate pukupuku pūtau iti, me ētahi atu. Kua arotahi ngā mahi rangahau ki te whakawhanake i ngā momo me ngā hanganga o te (S)-(+)-Camptothecin hei whakarei ake i tōna wairewa me te bioavailability, hei whakapai ake i tōna whai huatanga haumanu. Kua tūhuratia e ngā rangahau haumanu me ngā whakamātautau te whakamahinga o te (S)-(+)-Camptothecin hei kaihoko kotahi, hei whakakotahi rānei me ētahi atu kaihoko chemotherapy hei whakanui ake i ōna pānga antitumor me te whakaiti i ngā urupare kino. Heoi, he mea nui kia mōhio ko te (S)-(+)-Camptothecin ka whakaatu i ngā paitini me ngā pānga taha, me te aro turuki me te whakahaere tupato e ngā tohunga hauora. Kei te haere tonu te tūhuratanga o (S)-(+)-Camptothecin me ōna hua ki te whakatairanga i ngā whanaketanga o te maimoatanga mate pukupuku, e tuku ana i te tumanako mō ngā putanga rongoā pai ake me te kounga o te oranga mō ngā tūroro e whawhai ana ki ngā momo mate pukupuku.