Rosuvastatin Calcium CAS:147098-20-2 Kaihanga Kaiwhakarato

He aukati whiriwhiri te konupūmā Rosuvastatin i te HMG-CoA reductase. Ko te aukati HMG-CoA reductase te whākōkī e whakawhāiti ana i te tere o te whakawhiti hydroxy-3-methylglutaryl coenzyme A ki te valerate A (te mua o te cholesterol). Ko te wāhi matua o te mahi a te rosuvastatin ko te ate - ngā whekau e whai ana ki te whakaheke cholesterol. Ka whakanui ake a Rosuvastatin i te maha o ngā kaiwhakawhiwhi LDL ate i runga i te mata o te pūtau, ka whakatairanga i te mimiti me te catabolism o te LDL, ka aukati i te hanganga ate o te VLDL, ka whakaiti i te tapeke o ngā matūriki VLDL me te LDL. Ka taea e te konupūmā Rosuvastatin te aukati whakataetae i te methylglutaryl coenzyme A reductase ate, ā, ka whai hua anō hoki ki te whakaiti i te ngako. He roa te haurua-ora. Kāore he pānga nui o te ira tangata me te tau o ngā tūroro ki te metabolism o ngā rongoā.