Piridoksal-5′-phosphate monohydrate CAS:41468-25-1

Ko te Pyridoxal-5′-phosphate monohydrate, e mōhiotia ana ko te PLP, te momo hohe o te huaora B6. He coenzyme nui e uru ana ki te whānuitanga o ngā tauhohenga whākōkī i roto i te tinana. He mahi nui tā te PLP i roto i te pākia o ngā waikawa amino, te hanga neurotransmitter, me te hanga o te heme, he wāhanga o te hemoglobin.

He mahi a te PLP hei coenzyme mā te herea ki ngā whākōkī motuhake, me te āwhina i ngā tauhohenga matū. He mahi whakakorikori, e āwhina ana i te hurihanga o ngā matū maha, pērā i ngā waikawa amino, ki ngā hua rerekē. He mea nui te PLP i roto i te pākia o ngā waikawa amino, pērā i te hurihanga o te tryptophan ki te serotonin, te pakaru rānei o te glycine ki te serine.

Haunga tōna tūranga i roto i te pākia o ngā waikawa amino, kei roto hoki te PLP i te hanganga o ngā neurotransmitters pērā i te dopamine, te norepinephrine, me te gamma-aminobutyric acid (GABA). He mea nui ēnei neurotransmitters mō te mahi tika o te roro, ā, kei roto hoki i te whakahaere i te kare ā-roto, te hinengaro, me te tuku tohu i waenga i ngā pūtau io.

Hei tāpiritanga, he mea nui te PLP mō te hanga i te heme, he wāhanga o te hemoglobin e kitea ana i roto i ngā toto toto whero. Ko te hemoglobin te kawenga mō te kawe i te hāora puta noa i te tinana, e mea nui ai te PLP mō te pupuri i ngā taumata hāora noa me te whakarite kia tika te mahi a ngā momo okana me ngā kiko.

Nā tōna hiranga i roto i ngā tukanga matū koiora maha, i ētahi wā ka tūtohutia te tāpiringa PLP mō ngā tāngata whai mate hauora, ngoikore rānei e pā ana ki te pākia o te huaora B6. Kei te wātea mai i roto i te ahua tāpiringa, ā, ka taea te tohu e ngā kaiwhakarato hauora mō ngā hiahia motuhake.