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Empagliflozin CAS:864070-44-0 Kaihanga Kaihanga
Ko te Empagliflozin he puhui C-glycosyl kei roto he toenga beta-glucosyl he (4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl} roopu kei te pokapū anomeric. He konutai-glucose Ko te kaitautoko o te kaitautoko 2 e whakamahia ana hei taapiri mo te kai me te korikori tinana hei whakapai ake i te mana glycemic i roto i nga pakeke e mate ana i te mate huka momo 2. Kei a ia te mahi hei aukati i te konutai-glucose transport protein subtype 2 me te kaihoko hypoglycemic. He C-glycosyl. he pūhui, he etera kakara, he etera tetrahydrofuryl me tetahi mema o te monochlorobenzenes.
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Celecoxib CAS:169590-42-5 Kaihanga Kaihanga
Ko Celecoxib he mema o te karaehe o te pyrazoles ko te 1H-pyrazole ka whakakapihia ki nga waahi 1, 3 me te 5 e te 4-sulfamoylphenyl, trifluoromethyl me nga roopu p-tolyl, ia.He aukati cyclooxygenase-2, ka whakamahia ki te maimoatanga o te mate pukupuku.He mahi hei aukati i te cyclooxygenase 2, he geroprotector, he tarukino anti-inflammatory kore-steroidal me te analgesic kore-narcotic.He mema o toluenes, he sulfonamide, he mema o te pyrazoles me te pūhui organofluorine.
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Idebenone CAS:58186-27-9 Kaihanga Kaihanga
Ko te Idebenone he puhui pararopi no te whanau quinone, he rite ki te coenzyme Q-10.He momo rongoa i hangaia e Takeda Pharmaceutical Company mo te maimoatanga o te mate a Alzheimer me etahi atu ngoikoretanga o te hinengaro.Heoi, kaore enei i te tino ahunga whakamua e pa ana ki tenei tohu.Kei te whakamahia ano inaianei mo te maimoatanga o te ataxia a Friedreich me te painga pai ki te hypertrophy ngakau me te mahi neurological.
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Deflazacort CAS:14484-47-0 Kaihanga Kaihanga
Deflazacort (ingoa hokohoko Emflaza i roto i etahi atu) he glucocorticoid whakamahia hei anti-inflammatory me te immunosuppressant.No te roopu rongoa e kiia nei ko te corticosteroids.I etahi wa ka kiia ko te steroid a-waha. Ko te Deflazacort he prodrug hohekore e tere tere ana ki te tarukino kaha 21-desacetyl deflazacort.
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Citicoline(CDP Choline) CAS:33818-15-4 Kaihanga Kaituku
Ko te Citicoline he waikawa nucleic derivatives, i kitea e Geiger ka taea e te citicoline te whakaora i te whara o te roro i roto i nga whakamatautau kararehe i te 1956. He mea nui ki te whakauru o te lecithin, ma te whakatairanga i te whakawhitinga o te lecithin me te whakapai ake i te mahi roro.Ko nga whakamatautau e whakaatu ana ka taea e te citicoline te whakarei ake i nga taumata o te norepinephrine me te dopamine i roto i te punaha nerve matua, na reira ka taea e ia te rongoa i te mate cerebrovascular, te whara o te roro me te ngoikore o te hinengaro na nga take rereke, a kaore he paanga o te taha.
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Duloxetine HCL CAS:136434-34-9 Kaihanga Kaihanga
Duloxetine HCLhe serotonin whiriwhiri (5-HT) me te norepinephrine reuptake inhibitor (SSNRI) mo te whakahaere waha, a kua whakaaetia i tenei wa i te US me Uropi mo te maimoatanga o te mate pouri nui (MDD) me te mamae neuropathic peripheral mate huka (DPN).
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Ibandronate Sodium CAS:138844-81-2 Kaihanga Kaihanga
IKo te konutai bandronate (BONIVA) he bisphosphonate kei roto i te hauota e aukati ana i te resorption o nga wheua o te osteoclast.Kei a BONIVA ano nga mea e whai ake nei: lactose monohydrate, povidone, microcrystalline cellulose, crospovidone, waikawa stearic purea, colloidal silicon dioxide, me te wai para.Kei roto i te paninga kiriata papa he hypromellose, titanium dioxide, talc, polyethylene glycol 6000, me te wai parakore.
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Perindopril Erbumine CAS:107133-36-8 Kaihanga Kaituku
Ko te Perindopril erbumine he taapiri taapiri.Kei a ia te mahi hei kaihoko antihypertensive me te aukati EC 3.4.15.1 (peptidyl-dipeptidase A).Kei roto he perindopril(1-).
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TUDCA CAS:14605-22-2 Kaihanga Kaihanga
Ko te waikawa Tauroursodeoxycholic (TUDCA) he waikawa bile hydrophilic i whakahiatohia i roto i nga hepatocytes e te whakakotahitanga o te waikawa ursodeoxycholic (UDCA) me te taurine waikawa amino.Ko te UDCA, he mea hanga na te huakita whekau, kua whakaaetia e te FDA i te United States mo te maimoatanga o etahi mate ate cholestatic.Ka mahia e te tangata te TUDCA, engari ka kitea i roto i te maha o nga moni i roto i te papa o te pea.Ko te TUDCA he aukati matarohia o te ahotea endoplasmic reticulum (ER).
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L-Arginine Malate CAS:41989-03-1 Kaihanga Kaihanga
Ko te L-Arginine malate he whakakotahi i te L-arginine me te waikawa malic.Ko te L-arginine malate e tautoko ana i te paopaotanga pūngao me te awhina i te tinana ki te whakakore i te hauota taikaha.I muri i te tango i te waikawa arginine malic i roto i te oranga o ia ra, ka whai hua ki te whakaheke i te ngako me te mate taimaha.Ko te waahanga waikawa malic kei roto i te whakapai ake ka taea te whakatairanga i te peristalsis gastrointestinal, te awhina ki te whakapakari i te tere o te metabolism i roto i te tinana, me te whakaiti i te kohinga o te ngako tinana, ka pai ake te awhina me te tautoko mo te whakatutuki i te mate taimaha.
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Sitagliptin Phosphate CAS:654671-78-0 Kaihanga Kaituku
Sitagliptin PhosphateKo te pukapuka tuatahi te dipeptidyl peptidase IV te aukati mai i Merck mo te maimoatanga o te mate huka momo 2 kaore he taumaha me te mate o te hypoglycemia he rite ki te placebo.Ka mahi a Sitagliptin ma te whakarei ake i te punaha incretin o te tinana, e awhina ana ki te whakahaere i te huka ma te pa ki nga pūtau β me te α i roto i te pancreas.
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Tert-Butylamine CAS:75-64-9 Kaihanga Kaihanga
Ko te Tert-butylamine he amine aliphatic tuatahi ko te ethylamine ka whakakapihia e nga roopu methyl e rua i te waahi 1. He turanga whakakotahi o te tert-butylammonium.Ka whakamahia ano a Tert-Butylamine mo te hanga i nga otaota, ara, te terbacil me nga triazines terbutylazine , terbumeton, me te terbutryn me te ngarara (hei tauira, diafenthiuron).Kua tohua ano he pärönaki hei whakapumau mo nga whakapaipai.
