Empagliflozin CAS:864070-44-0 Kaihanga Kaiwhakarato

He aukati SGLT-2 hou, kaha, me te whiriwhiri a Empagliflozin, e whakapai ake ana i te whakahaere glycemic me ngā āhuatanga o te mate pāwera i roto i ngā kiore mate huka. Ko Empagliflozin (ingoa hokohoko Jardiance) he aukati i te konutai glucose co-transporter-2 (SGLT-2), ā, ka puta te huka i roto i te toto i roto i ngā whatukuhu me te whakakore i roto i te mimi. Ka taea e te Empagliflozin te matewai me te heke iho o te toto toto, ka hua ake he whanoke, he ngoikore rānei, ā, ka heke te mahi whatukuhu o ngā tūroro. Ko te mōrearea o ngā tūroro kaumātua, inā koa ko te hunga he ngoikore te mahi whatukuhu me ngā diuretics, te āhua nei he nui ake. E hiahiatia ana e te FDA a Boehring rāua ko Eli Lilly kia whakahaere i ētahi rangahau whai muri i te hokohoko e whā: te whakaoti i ngā whakamātautau hua cardiovascular tonu, ngā whakamātautau pharmacokinetics me pharmacodynamics tamariki, ngā whakamātautau haumaru me te whai huatanga tamariki, te whakamātautau paitini mō te rongoā (ina koa te pānga mō te mahi whatukuhu, te wheua me te tipu me te whanaketanga).