Te hanganga me te whakamahinga o Acetyl Octapeptide-3 CAS:868844-74-0

Ko te Acetyl Octapeptide-3 (CAS 868844-74-0) he peptide hangai rongonui i roto i te pūtaiao whakapaipai, e hokohokohia ana i raro i te ingoa hokohoko SNAP-8. Me wehewehea e tātou tōna hanganga me tōna whakamahinga.

1. Tuakiri me te Tikanga Mahi

· Tuakiri Matū:He peptide hangai kua whakapūmautia tēnei, ko te raupapa Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2. Ka whakarei ake te whakapūmautanga i tōna urunga ki te kiri me te pumau.

· Tikanga Matua:E kiia ana he "momo Botox ā-papa," ko tana mahi he aukati whakataetae. Ka whai i te pito N-terminal o te pūmua SNAP-25, he wāhanga matua i roto i te matatini SNARE e tika ana mō te tukunga o ngā neurotransmitters (pēnei i te acetylcholine) e tohu ana i te whakahekenga o te uaua.

· Pānga Matua:Mā te whakataetae ki te SNAP-25 tūturu mō tētahi tūranga i roto i te matatini SNARE, ka aukati i te hanganga o tētahi matatini mahi-katoa. Ka hua ake tēnei i te whakahekenga wāhanga o te tukunga o ngā neurotransmitter, ka heke iho te kaha me te auau o ngā whakahekenga uaua o te mata, ā, ka whakangawari i te āhua o ngā rārangi whakapuakanga, inā koa i te rae me te taha o ngā kanohi.

2. Ngā Aratohu Whakatakoto

He matū kaha engari he matū ngawari te Acetyl Octapeptide-3. He mea nui te hanganga tika mō te pumau me te whai huatanga.

A) Te Kukū i Manakohia:

· Kei waenganui i te taumata whakamahinga noa2% ki te 10%o tētahi otinga peptide kua whakananua i mua.

· Ko te nui o te peptide hohe i roto i te rauemi mata (he paura ma te lyophilized) ka whakapūmautia i te nuinga o te wā. Ka whakaratohia e ngā kaiwhakarato arumoni noa hei2%, 5% rāneite otinga kua rewa i mua (i roto i te wai, i te ranunga wai/glycerin rānei) kia māmā ake ai te hanga.

· Ko te kukū whakamutunga o te peptide hohe i roto i te hua whakamutunga ka ahu mai i0.0005% ki te 0.002% (5-20 ppm)Me whai tonu i ngā taunakitanga horopeta motuhake a tō kaiwhakarato rauemi mata.

B) Te wairewatanga me te waka:

· He tino wairewa ki te wai. He pai ake te hanga i roto i te wāhanga wai o te hua.

· Ko ngā waka e tika ana ko:

· Ngā hinu (tino noa)

· Ngā kirimi

· Ngā Kirimi me ngā Rōhi (me whakauru ki te wāhanga wai i mua i te whakapūtanga)

· Ngā Hinu Hinu Waiora

· Ngā Wairewa Rehu

C) pH me te Pūmautanga:

· Te Awhe pH Tino Pai:5.0 – 7.0Mā te hanga i roto i tēnei awhe ka mau te pumau o ngā matū me te hototahi ki te kiri.

· Āta karohia ngā taiao waikawa rawa (pH < 4) me ngā taiao kawakore rawa (pH > 8) mō ngā wā roa.

D) Te Pāmahana me te Tukatuka:

· Ārai i te wera. Hei ārai i te pirau:

· Tāpirihia ki te āhua wai i te āhua, i raro rānei40°C (104°F).

· Ko te wā tino pai hei tāpiri ko te whakamatao i te wai whakapūkara ki raro iho i te 40°C, me whakarewa noa rānei ki te wai i te pāmahana rūma mō ngā serum/kiri.

· Āta karohia te tukatuka i te pāmahana teitei pērā i te whakakī wera, ki te kore e whakaūtia e ngā raraunga pumau.

E) Ngā Kai Hototahi me te Mahi Tahi:

· Tino pai me: Ētahi atu peptide ārai-pakeketanga (hei tauira, Matrixyl, Argireline), waikawa hyaluronic, niacinamide, antioxidants (Huaora C me te E), ngā whakamakuku kiri.

· Ngā Huinga Whakakotahi:

· Me ētahi atu peptide neuromodulatory: He maha ngā wā ka honoa ki te Acetyl Hexapeptide-8 (Argireline) mō tētahi pānga aukati whānui, maha-whāinga.

· Me ngā peptide whakanui collagen: Mā te whakakotahi me ngā peptide pēnei i te Palmitoyl Tripeptide-1, te Matrixyl rānei ka ārai i ngā raina hihiri (mai i te nekehanga uaua) me ngā raina pūmau (mai i te ngaronga o te tautoko hanganga).

· Ārai: Ngā matū whakahāora, whakaiti rānei kaha. Kia tūpato ki ētahi matū ionic ka pā pea ki tōna wairewatanga, ki tōna āhua rānei.

F) Te Tiaki:

· Hei wāhanga wairewa-wai, me whai pūnaha tiaki whānui pakari te whakatakotoranga whakamutunga hei ārai i te tipu o ngā moroiti ka taea te whakangaro i te peptide.