Natamycin/Pimaricin CAS:7681-93-8 Kaihanga Kaiwhakarato

Ko te Pimaricin he tetraene macrocyclic i wehea tuatahitia mai i Streptomyces natalensis i te tau 1957. He whānui te kaha o te Pimaricin ki te patu i te rewena me ngā harore miro mā te herea motuhake ki te ergosterol hei aukati i te tipu o te harore. Kāore i rite ki ngā polyenes e pā ana, te nystatin me te filipin, kāore te pimaricin e whakarerekē i te urunga o te kiriuhi plasma. Ka whakamahia te Pimaricin i roto i te umanga kai hei maimoatanga mata o ngā tiihi hei aukati i te pokepokea ai. Ko te Natamycin he paturopi polyene hanga-rua. He ngoikore te wairewa o te Natamycin i te wai, ā, e kore e uru ki te epithelium corneal kāore i pakaru. Ko te Natamycin anake te kaihoko patu harore kua whakaaetia mō te whakamahi i runga i te kanohi, ā, ko te rongoā kanohi anake e wātea ana mō te rongoā i te keratitis harore. Ko te Natamycin, e mōhiotia ana ko te pimaracin, nō te whānau polyene o ngā paturopi; (he rōpū kaihoko patu harore e aro ana, e herea ana ki ngā sterols eukaryotic me te ergosterol), ā, he metabolite tuarua o Streptomyces natalensis.