Rainazolid CAS:165800-03-3

He whānuitia te whakamahinga o te Linezolid i roto i ngā mahi haumanu hei whakahaere i ngā mate kino o te huakita Gram-pai e ātete ana ki ētahi atu paturopi. He mea noa te tohu mō ngā mate kiri me ngā kiko ngohengohe, te niumōnia, te bacteremia, me ngā mate wheua i puta mai i te MRSA, VRE, me ētahi atu mate pukupuku maha-rongoā. Nā te kaha o te Linezolid ki te aro ki ēnei rauropi uaua ki te rongoā, he mea nui tēnei hei rongoā mō te whawhai ki ngā mate uaua. I roto i ngā wāhi hōhipera, he maha ngā wā ka whakamahia te linezolid mō te rongoā i ngā mate pukupuku i roto i te hōhipera me te niumōnia e pā ana ki te hauora nā te whānui o te mahi me te āhua haumaru pai. Mā tōna hanganga ā-waha ka taea te rongoā watea i waho o te hōhipera mō ētahi mate, ka whakaratohia he rongoā whai hua ki ngā tūroro mō ngā mate pukupuku raruraru. Hei tāpiri, ka whakamahia te linezolid hei rongoā mō te mate kohi me ētahi atu mate pukupuku mycobacterial hei wāhanga o ngā tikanga rongoā whakakotahi. Nā tōna tikanga mahi ahurei me te urunga pai ki roto i te kiko, he mea nui tēnei hei tāpiri atu ki ngā taputapu mō te rongoā i te mate kohi ātete-rongoā me ngā mate pukupuku mycobacterial kāore i te kohi. I roto i ngā wāhi rangahau, ka whakamahia te linezolid hei paerewa tohutoro i roto i te whakamātautau ngoikore o te patu huakita hei aromatawai i te aro o ngā momo huakita ki tēnei paturopi. Mā te whakatau i te kukū iti rawa o te aukati (MIC) o te linezolid ki ngā huakita motuhake, ka taea e ngā kairangahau te ārahi i ngā rautaki maimoatanga tika me te aroturuki i ngā tauira ātete. I te nuinga o te wā, he mahi nui tā te linezolid i roto i te whakahaere i ngā mate kitakita Gram-pai uaua, e tuku ana i tētahi kōwhiringa maimoatanga kaha me te pono ki ngā tākuta ki ngā mate pukupuku ātete-rongoa. Nā tōna whai huatanga kua whakapumautia, tōna manawanui, me tōna whānui o te whakamahinga, he mea nui tēnei hei wāhanga o te pakanga ki ngā mate pipiri, inā koa ko ērā i puta mai i ngā huakita ātete-maha-rongoa.