Ibandronate Sodium CAS:138844-81-2 Kaihanga Kaihanga

I whakamahia te konutai Ibandronate ki te ako i tana paanga ki te tipu me te ultrastructure o Leishmania me Giardia e te whakatipuranga o nga pihinga kukū.Kua whakamahia ano hoki hei whakamarama i te huarahi e uru ai nga bisphosphonates hauota (N-BPs) ki roto i te cytosol me te aukati i to raatau molecular target.Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM).Ko te konutai Ibandronate ano hoki he aukati whakaheke wheua.Kua tirotirohia mo nga paanga anti-tumor in vitro, penei i te whakauru apoptosis, te aukati i te tipu o te pūtau, te aukati i te whanonga whakaeke, me te aukati i te angiogenesis me tana mahi in vivo i roto i nga momo mate pukupuku tae atu ki nga mate pukupuku u me te prostate.