Fmoc-Arg(Tos)-OH CAS:83792-47-6

He mahi nui tā te Fmoc-Arg(Tos)-OH i roto i te hanga peptide, inā koa ka hiahiatia he tiaki tika mō te hauota guanidine i roto i te arginine. Ka tiakina e te rōpū tiaki Fmoc te rōpū amino, ka whakarite i ngā tauhohenga whiriwhiri i te wā e honoa ana te peptide, ko te rōpū tosyl i runga i te hauota guanidine e whakarato ana i tētahi atu paparanga tiaki. Ka whakamahia e ngā kairangahau te Fmoc-Arg(Tos)-OH mō te hanga peptide me ngā whakarerekētanga guanidine motuhake, e awe ana i ā rātou mahi koiora. Mā te huarahi tiaki rua ka taea te whakahaere i te tauhohenga guanidine, ka whai hua ai tēnei matū ki te hoahoa i ngā peptide mō ngā rangahau antimicrobial, te bioconjugation, me te matū rongoā. Ko te hototahi o te Fmoc-Arg(Tos)-OH me ngā tikanga hanga peptide paerewa, tae atu ki te hanga peptide totoka-wāhanga (SPPS), ka whakarei ake i tōna whai huatanga. Ka kitea te tono o tēnei matū ki te hanga peptide mō ngā whakamātautau koiora, te kimi rongoā, me te whakawhanaketanga o ngā rauemi e hangai ana ki te peptide. Mā te tango whakahaere i ngā rōpū tiaki ka taea te whakauru rautaki o te arginine me te guanidine kua whakarerekētia, ka whai wāhi ki te kanorau o ngā peptide ka taea te hanga. Hei whakarāpopototanga, ko te Fmoc-Arg(Tos)-OH he taputapu motuhake, he maha hoki ngā whakamahinga i roto i te matū peptide, e whakamana ana i ngā kairangahau ki te tūhura me te whakarerekē i te tauhohenga guanidine mō ngā momo tono pūtaiao me te rongoā.