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Ethyl oxalyl monochloride CAS: 4755-77-5
Ko te Ethyl oxalyl monochloride he matū waro nui e tohuhia ana e te rōpū ethyl e piri ana ki te wāhanga oxalyl, e rua ngā rōpū carbonyl me te ngota chlorine kotahi. Me te tātai ngota C5H7ClO3, e mōhiotia whānuitia ana tēnei matū hei takawaenga whai hua i roto i te hanganga waro, inā koa i roto i ngā ahumahi rongoā me te ahuwhenua. Ko tōna kaha tauhohe ahurei e ahu mai ana i ōna mahi oxalyl me te chlorinated, e āhei ai ia ki te whai wāhi ki ngā huringa matū. Kua tūhuratia e ngā kairangahau te ethyl oxalyl monochloride mō ōna tono pea ki te hanga i ngā ngota matatini me ngā mahi koiora rerekē.
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DL-4-Chlorophenylglycine CAS:6212-33-5
He matū te DL-4-Chlorophenylglycine kua nui te aro ki ngā mara o te matū rongoā me te rongoā. Hei matū glycine derivative, kei roto he rōpū chlorophenyl, e whakarei ake ana i ōna āhuatanga here me te mahi koiora. Kua rangahaua tēnei matū mō ōna tono pea ki te rongoā i ngā mate pūnaha io, inā koa mā te whakarerekē i ngā kaiwhakawhiwhi glutamate. Mā te hanganga ahurei o te DL-4-Chlorophenylglycine ka taea hoki e ia te mahi hei hoariri, hei kaiwhakahohe rānei i runga i tōna taiao, ka waiho hei kaitono maha mō te rangahau i ngā maimoatanga neuropharmacological. Ko tōna hanganga me tōna āhua kei te noho tonu hei wāhanga rangahau kaha.
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DRONEDARONE HYDROCHLORIDE CAS:141625-93-6
Ko te Dronedarone hydrochloride he rongoā antiarrhythmic e whakamahia ana mō te whakahaere i te atrial fibrillation me te atrial flutter. He mea hanga mai i te amiodarone, i whakawhanakehia hei whakarato i ngā painga rongoā rite tonu me te whakaiti i ētahi o ngā pānga kino e pā ana ki te amiodarone, inā koa ko ōna paitini tairoi me te pūkahukahu. Ka mahi te Dronedarone mā te whakaroa i te pūmanawa mahi me te wā ātete i roto i ngā kiko o te ngākau, te whakatau i te manawataki o te ngākau, me te whakaiti i te mōrearea o te noho hōhipera nā ngā mate cardiovascular. Kua whakaaetia mō te whakamahinga haumanu i roto i ngā whenua maha, ko te dronedarone he whanaketanga nui i roto i te whakahaere rongoā o ngā arrhythmias atrial.
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waikawa valproic CAS:99-66-1
Ko te waikawa Valproic, e mōhiotia ana ko te waikawa 2-propylpentanoic, he rongoā whānuitia hei ārai i te haurangi me te whakaū i te wairua, e tohua ana mō te rongoā i te mate haurangi me te mate bipolar. I kitea i te tekau tau atu i 1960, ka mahi mā te whakanui ake i ngā taumata o te waikawa gamma-aminobutyric (GABA) i roto i te roro, he neurotransmitter nui e āwhina ana ki te whakahaere i te whakaohooho neuronal. Kua mōhiotia te waikawa Valproic ehara i te mea mō tōna whai huatanga ki te whakahaere i ngā haurangi engari mō tōna tūranga hoki ki te aukati i ngā migraines me te rongoā i ētahi āhuatanga hinengaro. Nā tōna āhua rongoā pai, he mea nui hei rongoā i roto i te neurology me te psychiatry.
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Konutai Valproate CAS:1069-66-5
Ko te Sodium valproate, te tote konutai o te waikawa valproic, he rongoā ārai-ohorere me te rongoā whakaū-hinengaro e whakamahia ana i roto i te rongoā o te mate haurangi me te mate bipolar. Ka mahi mā te whakanui ake i ngā taumata o te waikawa gamma-aminobutyric (GABA) i roto i te roro, he neurotransmitter e whai wāhi nui ana ki te whakaiti i te whakaohooho neuronal. I whakaaetia i te mutunga o te rautau 20, e mōhiotia ana te sodium valproate mō tōna whai huatanga puta noa i ngā momo hopukanga, ā, e whakamahia ana hoki i roto i te ārai i te migraine. Nā tōna āhua rongoā pai kua waiho hei whiringa rongoā nui i roto i te neurology me te psychiatry.
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ETHYL 5-AMINOBENZOFURAN-2-CARBOXYLATE CAS:174775-48-5
Ko te Ethyl 5-aminobenzofuran-2-carboxylate he matū e pā ana ki te akomanga o ngā benzofuran derivatives, he mea nui ki te matū rongoā nā te whānuitanga o ā rātou mahi koiora. Kei roto i tēnei matū he rōpū mahi ethyl ester me te whakakapinga amino i runga i te mowhiti benzofuran, e hanga ana hei poraka hanga maha mō te hanga i ngā ngota koiora. Kua arohia te Ethyl 5-aminobenzofuran-2-carboxylate i roto i ngā rangahau rongoā mō ōna tono pea ki te whakawhanake i ngā kaihoko rongoā hou, inā koa i roto i ngā wāhanga pēnei i ngā maimoatanga anti-inflammatory, analgesic, antimicrobial rānei, nā ngā āhuatanga hanganga ahurei e tukuna ana e te hanganga benzofuran.
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Diethyl benzylmalonate CAS:607-81-8
He matū waro nui te Diethyl benzylmalonate e whakamahia whānuitia ana i roto i te matū hanga, inā koa i roto i te whakarite i ngā momo rongoā me ngā matū ahuwhenua. Kei roto i tēnei waikawa malonic ngā rōpū ethyl ester e rua me te benzyl substituent, e whakarei ake ana i tōna kaha ki te tauhohe i roto i ngā tauhohenga whakakapinga nucleophilic. He poraka hanga maha ngā mahi a te Diethyl benzylmalonate i roto i te hanganga o ngā ngota ngota kaha koiora, tae atu ki ngā takawaenga matua i roto i te whanaketanga rongoā. Nā tōna hanganga ahurei me ōna āhuatanga mahi ka waiho hei matū nui i roto i te matū rongoā, e āhei ai ngā kaimātai matū ki te tūhura i ngā ara hanga rerekē mō te whakawhanake i ngā rongoā auaha.
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Indazole CAS:271-44-3
He matū kakara bicyclic te Indazole, he mowhiti pyrazole e rima ngā mema kua honoa ki te mowhiti benzene e ono ngā mema. E mōhiotia ana tēnei hanganga heterocyclic mō ōna mahi koiora kanorau me ngā tono pea i roto i te matū rongoā. Kua aro nui te Indazole me ōna hua nā te mea he maha ngā āhuatanga rongoā, pērā i te ārai-mumura, te ārai-matepukupuku, me ngā pānga antimicrobial. He tūāpapa nui te matū i roto i te whanaketanga rongoā, inā koa i roto i te hoahoa o ngā rongoā hou e aro ana ki ngā mate maha. Kei te haere tonu te rangahau ki te tūhura i ngā tikanga hanga me ngā pānga koiora e pā ana ki te indazole.
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ETHYL 5-NITROBENZOFURAN-2-CARBOXYLATE CAS:69604-00-8
He matū nui te Ethyl 5-nitrobenzofuran-2-carboxylate i roto i te ao matū waro, inā koa i roto i te ao o ngā matū heterocyclic. Hei benzofuran kua whakakapia ki te nitro, he āhuatanga matū ahurei me ngā mahi koiora e waiho ana hei ūnga whakamīharo mō te rangahau rongoā. Mā te noho mai o te rōpū nitro ka whakarei ake i tōna kaha urupare, ka taea ai te whakamahi i roto i te hanganga o ngā rongoā hou. Kua arohia te Ethyl 5-nitrobenzofuran-2-carboxylate mō tōna whakamahinga pea ki te whakawhanake i ngā kaihoko anti-inflammatory, antimicrobial, me te anti-cancer, e whakaatu ana i tōna hiranga ki te whakatairanga i te matū rongoā me ngā rautaki kimi rongoā.
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4-Bromophenylacetone CAS:6186-22-7
Ko te 4-Bromophenylacetone he ketone kakara e tohuhia ana e te bromine substituent i runga i te mowhiti phenyl, me te rōpū mahi acetone. Kua arohia tēnei matū i roto i te hanganga rauropi nā tōna whai huatanga hei poraka hanga i roto i te whanaketanga o ngā ngota matatini ake, tae atu ki ngā rongoā me ngā matū ahuwhenua. Ko te aroaro o te ngota bromine e whakarei ake ana i tōna āhua electrophilic, e whakahaere ana i ngā tauhohenga kanorau i roto i ngā ara hanga. Hei tāpiri, kua whakaatuhia e te 4-bromophenylacetone ngā mahi koiora pea, e waiho ana hei kaupapa hiahia i roto i te matū rongoā mō te tūhuratanga me te tono atu i roto i te kitenga rongoā.
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4-Hydroxyphenylacetone CAS:770-39-8
Ko te 4-Hydroxyphenylacetone he ketone kakara e whakaatu ana i tētahi rōpū hydroxyl e piri ana ki te mowhiti phenyl me tētahi wāhanga acetone. E mōhiotia ana tēnei pūhui mō ōna whakamahinga kanorau i roto i te hanganga rauropi me te matū rongoā. He takawaenga nui tēnei i roto i te whakarite i ngā momo rongoā, ngā matū ahuwhenua, me ngā matū pai. Mā te noho mai o te rōpū hydroxy ka whakarei ake i tōna tauhohenga, ā, ka taea te whakarerekē atu, ka waiho hei tūāpapa nui mō te whanaketanga rongoā. Kua whakaatuhia e te rangahau ki te 4-hydroxyphenylacetone ōna mahi koiora pea, tae atu ki ngā āhuatanga antioxidant me te anti-inflammatory, e whai wāhi ana ki tōna hiranga i roto i ngā rangahau rongoā.
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3-(4-Chlorbutyl)-1H-indol-5-carbonitril CAS:143612-79-7
Ko te 3-(4-Chlorobutyl)-1H-indol-5-carbonitrile he indole derivative e tohuhia ana e te huinga ahurei o ngā rōpū mahi indole me te nitrile, me te mekameka taha chlorobutyl. Kua arohia tēnei matū i roto i te mara o te matū rongoā nā ōna mahi koiora pea, tae atu ki ngā āhuatanga antimicrobial, anti-inflammatory, me te anti-cancer. Ko te indole scaffold he pou tuara maha mō te hoahoa rongoā, i te mea ko te aroaro o te rōpū chlorobutyl ka whakarei ake i tōna lipophilicity, ka whakapai ake pea i te bioavailability. Ko te whāinga o te rangahau tonu ko te tūhura i ngā tono rongoā me ngā tikanga mahi e pā ana ki tēnei matū.
