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Waikawa 2-Hydroxyisonicotinic CAS:90-33-5
Ko te waikawa 2-Hydroxyisonicotinic he mea hanga mai i te waikawa isonicotinic, e tohuhia ana e te aroaro o te rōpū hydroxyl i te tūranga tuarua o te mowhiti pyridine. He maha ngā mahi koiora o tēnei pūhui, tae atu ki ngā āhuatanga ārai mate me te ārai mumura pea. Nā tōna hanganga ōrite ki ētahi atu mea hanga mai i te waikawa nicotinic, he mea whakamere tēnei mō te whakawhanaketanga rongoā. Kei te tūhuratia e ngā kairangahau ōna tono i roto i te matū rongoā, inā koa i roto i te rongoā i ngā mate maha. He poraka hanga te pūhui mō te hanga i ngā ngota uaua ake, ā, kua arohia i roto i ngā mara o te hanga matū waro me te rangahau rongoā.
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Metila 2-aminopyridine-4-carboxylate CAS:6937-03-7
Ko te Methyl 2-aminopyridine-4-carboxylate he pyridine derivative kei roto ko te rōpū amino kei te tūranga-2 me te carboxylate ester kei te tūranga-4, me te rōpū methyl e piri ana ki te waikawa carboxylic. He mea nui tēnei matū ki te matū rongoā nā te mea he maha āna mahi koiora pea, tae atu ki ngā āhuatanga antimicrobial me te anti-inflammatory. Ko te whakaritenga ahurei o ngā rōpū mahi ka whakarei ake i tōna tauhohenga me tōna whai huatanga hei poraka hanga maha i roto i te hanga rauropi. Kei te haere tonu te rangahau ki te tūhura i ōna tono i roto i te whanaketanga rongoā me ētahi atu mara, e whakaatu ana i tōna hiranga i roto i te ao o te matū heterocyclic.
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Tofacitinib Citrate CAS:540737-29-9
Ko te Tofacitinib citrate he aukati Janus kinase (JAK) ā-waha e whakamahia ana mō te rongoā i te rumatiki rheumatoid, te rumatiki psoriatic, me te colitis ulcerative. Ko tana mahi mā te aukati i ngā whākōkī JAK1 me JAK3, e whai wāhi nui ana ki ngā ara tohu o ngā momo cytokine e uru ana ki ngā tukanga mumura. Mā te tātai ngota C16H20N6O5S·C6H8O7, kua whakaatuhia e te tofacitinib citrate te whai huatanga ki te whakaiti i te mumura me te whakapai ake i te kounga o te oranga o te tūroro. Kua whakaaetia mō te whakamahinga haumanu i roto i ētahi whenua, ko te whāinga o ngā rangahau tonu ko te tūhura i ōna tono rongoā whānui, te kōtaha haumaru, me ngā putanga roa i roto i ngā momo mate autoimmune.
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Cyclen CAS:294-90-6
Ko te Cyclen, 1,4,7,10-tetraazacyclododecane rānei, he matū polyamine e mōhiotia ana mō tōna hanganga huringa ahurei e whakaatu ana i ngā ngota hauota e whā kua whakauruhia ki roto i tētahi mowhiti tekau mā rua ngā mema. Mā te tātai ngota C8H16N4, he mea nui te mahi a te cyclen hei ligand i roto i te matū taunga nā tōna kaha ki te hanga matatini pumau me ngā konganuku whakawhiti. Nā ōna āhuatanga chelating ka whai hua i roto i ngā tono maha, tae atu ki te matū rongoā, ngā rongoā irirangi, me te matū supramolecular. Kei te rangahau tonuhia te pūmanawa o te cyclen i roto i ngā pūnaha tuku rongoā me te whanaketanga o ngā kaihoko whakaahua kua tohua, me te whakanui i tōna hiranga i roto i ngā pūtaiao taketake me ngā pūtaiao tono.
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![4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane CAS:57280-22-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT317.png)
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane CAS:57280-22-5
Ko te 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane he matū waro bicyclic e tohuhia ana e tōna hanganga ahurei kei roto ko ngā hononga etera e rua me ngā ngota hāora e toru i roto i te anga bicyclic. Me te tātai ngota C10H16O3, ka whakaatuhia e tēnei matū ngā āhuatanga matū whakamere nā te aroaro o ngā rōpū methyl me ngā mahi etera. Ka whai wāhi tōna hanganga bicyclic ki tōna pumau me te tauhohenga, ka waiho hei kaitono pea mō ngā tono maha i roto i te matū waro hanga. Ka tūhuratia e te rangahau tōna whakamahinga i roto i te hanganga o ngā ngota uaua ake me tōna pūmanawa hei poraka hanga i roto i ngā pūtaiao rongoā me ngā rauemi.
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![4-Kōro-7-[(4-metilfenil)hāronira]-7H-piroro[2,3-d]pirimidina CAS:479633-63-1](https://cdn.globalso.com/xindaobiotech/VMLV8UWXAZ0XBLS6M290.png)
4-Kōro-7-[(4-metilfenil)hāronira]-7H-piroro[2,3-d]pirimidina CAS:479633-63-1
He matū hangai te 4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine e mōhiotia ana mō ōna whakamahinga rongoā pea. He hanganga ahurei tōna e whakauru ana i te matua pyrrolopyrimidine, he whakakapinga chloro, me te wāhanga sulfonyl e hono ana ki te rōpū para-methylphenyl. Tērā pea ka whai wāhi tēnei hanganga ki tōna mahi koiora, ka waiho hei kaitono mō te rangahau i ngā wāhanga pēnei i te oncology, te mumura rānei. Kei te haere tonu ngā rangahau hei tūhura i ōna tikanga mahi, te whai huatanga, me te kōtaha haumaru, me te whāinga ki te tautuhi i ōna whakamahinga rongoā pea i roto i ngā momo āhuatanga hauora.
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3-Pyridinesulfonyl chloride CAS:16133-25-8
He matū waro nui te 3-Pyridinesulfonyl chloride, ko tōna tātai ngota C6H6ClN O2S. He matū sulfonyl chloride tēnei i ahu mai i te pyridine, kei roto ko te rōpū mahi sulfonyl chloride e piri ana ki te tuatoru o ngā tūranga o te mowhiti pyridine. Ko tēnei matū te mea matua e whakamahia ana i roto i te hanga waro hei matū mō te whakauru i ngā rōpū sulfonyl ki roto i ngā momo matū. Nā tōna kaha ki te uru atu ki ngā tauhohenga whakakapinga nucleophilic, e whai hua ai ki te hanga sulfonamides me ētahi atu ngota koiora. Hei tāpiri, he pea ngā tono a te 3-pyridinesulfonyl chloride ki ngā rongoā me ngā matū ahuwhenua.
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2-Aminoisonicotinic acid CAS:13362-28-2
Ko te waikawa 2-Aminoisonicotinic he pyridine derivative, he isomer o te waikawa nicotinic, e tohuhia ana e te aroaro o te rōpū amino i te tūranga-2 o te hanganga waikawa isonicotinic. Me te tātai ngota C6H6N2O2, he āhuatanga matū whakamere tēnei pūhui, ā, kua arohia ki te matū rongoā mō ōna mahi koiora pea, tae atu ki ngā pānga antimicrobial me te anti-inflammatory. Mā ngā mahi a te waikawa amino me te waikawa carboxylic ka taea te whakarerekē i ngā momo matū, ka waiho hei takawaenga nui i roto i te hanganga rauropi. Kei te tūhuratia tonutia tōna pūmanawa rongoā, e whakaatu ana i tōna hiranga ki te whanaketanga rongoā me ētahi atu tono.
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2-Amino-4-cyanopyridine CAS:42182-27-4
Ko te 2-Amino-4-cyanopyridine he matū pyridine e tohuhia ana e te rōpū amino i te tūranga-2 me te rōpū cyano i te tūranga-4 o te mowhiti pyridine. Mā te tātai ngota C6H4N4, ka whakaatuhia e tēnei matū ngā āhuatanga matū whakamīharo me ngā mahi koiora pea. Kua rangahauhia mō āna tono i roto i te matū rongoā, inā koa i roto i te whakawhanaketanga rongoā nā te mea ka taea te patu huakita, te patu harore, me te patu mumura. Mā te noho mai o ngā rōpū mahi e rua ka whakarei ake i tōna tauhohenga, ka waiho hei takawaenga nui i roto i te hanganga rauropi. Kei te haere tonu te rangahau ki te tūhura i tōna whānuitanga i roto i ngā mara maha tae atu ki ngā rongoā me ngā matū ahuwhenua.
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2-(4-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid, ethyl ester, hydrochloride (1:1) CAS:399017-10-8
Ko te 2-(4-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid, ethyl ester, hydrochloride (1:1) he matū i ahu mai i te thiazole, e tohuhia ana e tōna hanganga ahurei kei roto ko te rōpū hydroxyl, te rōpū methyl, me te ethyl ester. Kua piki ake te hiahia o tēnei matū ki te matū rongoā nā ōna mahi koiora pea, pērā i ngā āhuatanga ārai-mumura me te ārai-paturopi. Ka whakarei ake te āhua tote hydrochloride i te wairewa me te pumau, ka āwhina i tōna whakamahinga i roto i ngā hanganga rongoā. Kei te haere tonu te rangahau ki te tirotiro i tōna whai huatanga i roto i ngā tono rongoā maha, ka waiho hei kaitono whai hua mō ētahi atu rangahau i roto i te whanaketanga rongoā me te arotautanga mata.
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3-Methyl-4-nitropyridine N-Oxide CAS:1074-98-2
Ko te 3-Methyl-4-nitropyridine N-oxide he matū pyridine e tohuhia ana e te rōpū methyl i te tūranga-3 me te rōpū nitro i te tūranga-4 o te mowhiti pyridine, me te rōpū mahi N-oxide. He āhuatanga matū me ngā mahi koiora rongonui kei roto i tēnei matū, ā, he mea whakamere ki ngā momo mara pēnei i te matū rongoā me ngā matū ahuwhenua. Mā te noho mai o ngā rōpū nitro me te N-oxide ka taea te whakarei ake i tōna tauhohenga me ngā tono pea i roto i te matū hanga. Kei te haere tonu te rangahau ki te tūhura i te whai huatanga o te matū i roto i te kimi rongoā me ētahi atu tono, e whakaatu ana i tōna hiranga i roto i te matū waro o nāianei.
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(1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine CAS:511534-44-4
He matū chiral nui te (1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine, he rōpū mahi sulfonamide me te tuara diphenylethylene. Mā te tātai ngota C16H20N2O2S, he mahi nui tā tēnei matū i roto i te hanga me te whakaterenga kore taurite nā tōna kaha ki te hanga taiao chiral pumau. Mā tōna hanganga ahurei ka taea ngā tauhohenga whiriwhiri, ka whai hua ai i roto i te whanaketanga o ngā rongoā me ngā matū ahuwhenua. Kei te tūhuratia tonutia e ngā rangahau ōna tono i roto i te hanga stereoselective, e whakaatu ana i tōna pūmanawa hei ligand i roto i te matū organometallic me te whakawhānui ake i tōna hiranga i roto i te hanga waro hou.
