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2,4,5-trifluorobenzyl bromide CAS:157911-56-3
Ko te 2,4,5-Trifluorobenzyl bromide he matū waro tino tauhohe, nō te kāwai aryl halides. Ko tōna hanganga ngota e tohuhia ana e te mowhiti benzene kua whakakapia ki ngā ngota fluorine e toru i ngā tūranga 2, 4, me te 5, me te ngota bromine e piri ana ki te tūranga benzylic. Mā tēnei tauira whakakapinga ka hua ake he ngota he āhua electrophilic kua whakarei ake, ka waiho hei matū whai hua i roto i te hanganga waro.
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(2-Kōro-5-iodophenyl)(4-fluorophenyl)methanone CAS:915095-86-2
Ko te matū (2-chloro-5-iodophenyl)(4-fluorophenyl)methanone e tū ana hei takawaenga matua i roto i te ao matū waro, e whakamanamana ana i tētahi hanganga motuhake e tohuhia ana e te hanumitanga o tētahi mowhiti benzene me ngā whakakapinga e rua he rerekē ngā āhuatanga hiko: he rōpū 2-chloro-5-iodo me tētahi wāhanga 4-fluorophenyl. Nā tēnei whakaritenga ahurei ka whakawhiwhia te ngota ki te whānuitanga o te tauhohenga matū, ka waiho hei kaitono e rapuhia ana mō ngā tono maha i roto i ngā mara o te rongoā me te pūtaiao rauemi.
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(S)-(2-Kōro-5-iodophenyl)(4-(tetrahydrofuran-3-ilokisi)phenyl)methanone CAS:915095-87-3
Ko te (S)-(2-chloro-5-iodophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)methanone he ngota waro matatau e whakaatu ana i ngā rōpū mahi maha, e whai wāhi ana ki tōna matū matatini me ngā tono kanorau. Ko tōna hanganga matua he mowhiti benzene kua whakapaipaihia ki ngā whakakapinga e rua: he rōpū 2-chloro-5-iodo me te wāhanga 4-(tetrahydrofuran-3-yloxy)phenyl. Ko te hua o tēnei whakaritenga he pūhui me te huinga taurite o ngā rōpū tuku-irahiko me ngā rōpū tango-irahiko, e tino pā ana ki tōna whanonga matū.
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1-(3,5-Dichlorophenyl)-2,2,2-trifluoroethanone CAS:130336-16-2
Ko te 1-(3,5-Dichlorophenyl)-2,2,2-trifluoroethanone he matū organochlorine kei roto he rōpū trifluoromethyl e piri ana ki te tuara ethanone. Ko te noho mai o te rōpū trifluoromethyl ka hoatu he āhuatanga ahurei ki te ngota, pērā i te pikinga o te lipophilicity me te taumata teitei o te electronegativity, ka pā nui ki tōna tauhohenga me te pumau.
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3-(3-iodopropyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one CAS:148870-57-9
Ko te 3-(3-Iodopropyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one he matū matū matatini e pā ana ki te whānau benzazepine. Kei roto ko te mowhiti benzene e whitu ngā mema e honoa ana ki te mowhiti azepine e toru ngā mema, me ngā rōpū methoxy e rua e piri ana ki ngā tūranga 7 me te 8 o te mowhiti benzene. Kei roto hoki i te matū he mekameka iodoalkyl i te tūranga 3 o te mowhiti azepine.
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7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one CAS:73942-87-7
Ko te 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one he matū bicyclic nō te whānau benzazepine. Kei roto ko tētahi mowhiti benzene e whitu ngā mema kua honoa ki tētahi mowhiti azepine e toru ngā mema, me ngā rōpū methoxy e rua e piri ana ki ngā tūranga 7 me te 8 o te mowhiti benzene. Kei roto hoki i te matū he rōpū ketone kei te tūranga 2 o te mowhiti azepine.
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![(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride CAS:866783-13-3](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG275.png)
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride CAS:866783-13-3
Ko te (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride he matū rauropi chiral e whakaatu ana i te matua benzocyclobutane me ngā rōpū methoxy e rua e piri ana ki ngā tūranga 4 me te 5 o te mowhiti cyclobutane. Kei roto hoki i te matū he rōpū methylamino e piri ana ki te tūranga 1 o te mowhiti cyclobutane, e hanga ana i tētahi hononga waro-hauota tāpiri.
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Naphthalene, 1-cyclopropyl-4-isothiocyanato- CAS:878671-95-5
Ko te Naphthalene, 1-cyclopropyl-4-isothiocyanato- he matū i ahu mai i te naphthalene, he hauwaiwai kakara polycyclic kei roto ko ngā mowhiti benzene e rua kua hanumi. I roto i tēnei matū, ka piri te rōpū cyclopropyl ki te tūranga 1 o te matua naphthalene, ko te rōpū isothiocyanato ia ka piri ki te tūranga 4.
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3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro CAS:878671-96-6
Ko te 3H-1,2,4-Triazole-3-thione, 5-amino-4-[4-cyclopropyl-1-naphthalenyl]-2,4-dihydro, e mōhiotia whānuitia ana ko te 5-amino-4-[4-cyclopropyl-1-naphthalenyl]-1,2,4-triazole-3-thione, ko te TTTA rānei, he matū heterocyclic e whakaatu ana i te matua triazole e hono ana ki te mowhiti naphthalene. Ko te mowhiti triazole he mowhiti e rima ngā mema kei roto e toru ngā ngota hauota, ko te mowhiti naphthalene he mowhiti kakara e ono ngā mema kua honoa ki te mowhiti benzene tuarua.
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Losartan CAS:114798-26-4
He rongoā whakaheke toto a Losartan nō te akomanga o ngā aukati i te toto o te angiotensin II (ARB). Mā te aukati i te mahi a te angiotensin II, he mea whakapūmau toto kaha e whai wāhi nui ana ki te whakahaere i te toto toto. Mā te aukati i te here o te angiotensin II ki ōna kaiwhakawhiwhi, ka whakaitihia e te losartan te whakapūmau toto me te whakaiti i te tukunga o te aldosterone, he homoni e whai wāhi ana ki te pupuri i te konutai me te wai.
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(1R,2R)-1,2-Cyclohexanedimethanol CAS:65376-05-8
He rongoā whakaheke toto a Losartan nō te akomanga o ngā aukati i te toto o te angiotensin II (ARB). Mā te aukati i te mahi a te angiotensin II, he mea whakapūmau toto kaha e whai wāhi nui ana ki te whakahaere i te toto toto. Mā te aukati i te here o te angiotensin II ki ōna kaiwhakawhiwhi, ka whakaitihia e te losartan te whakapūmau toto me te whakaiti i te tukunga o te aldosterone, he homoni e whai wāhi ana ki te pupuri i te konutai me te wai.
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Waikawa acetic, 2-((5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl)thio)-, ethyl ester CAS:1158970-52-5
Ko te waikawa acetic, 2-((5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl)thio)-, ethyl ester he matū matū waro matatini e tito ana i te waikawa acetic ester kua mahi tahi me te mowhiti 1,2,4-triazole me te wāhanga naphthalene kua whakakapia ki te cyclopropyl. Ko te mowhiti triazole he mowhiti heterocyclic e rima-mema kei roto e toru ngā ngota hauota, ko te mowhiti naphthalene he mowhiti kakara e ono-mema kua honoa ki te mowhiti benzene tuarua.
