Diammineplatinum(II) nitriteCAS:14286-02-3

He rongoā rongoā whānui te Cisplatin hei rongoā i ngā momo mate pukupuku, tae atu ki ngā mate pukupuku o te testicle, te ovarian, te pūkahukahu, me te pūkahukahu. Ka mahi mā te hanga hononga whakawhiti i roto i te DNA, ka ārai i te tāruarua me te tuhi DNA, ka mutu ka puta te apoptosis i roto i ngā pūtau mate pukupuku. Nā tōna whai huatanga ki te rongoā i ētahi momo mate pukupuku kua waiho hei tetahi o ngā rongoā mate pukupuku tino nui me te whānui e whakamahia ana i roto i te mahi haumanu. Haunga tōna whakamahinga hei rongoā rongoā, kua rangahauhia hoki te cisplatin mō ōna tono pea i roto i te mara o te matū rongoā. Kua arotahi ngā mahi rangahau ki te whakawhanake i ngā rongoā hou e ahu mai ana i te platinum me te whai huatanga pai ake, te whakaiti i te paitini, me te whānuitanga o te mahi ki ngā momo mate pukupuku rerekē. I tua atu, kua rangahauhia hoki te cisplatin mō tōna whakamahinga pea i roto i te rongoā whakakotahi me ētahi atu rongoā anticancer hei whakarei ake i ngā putanga maimoatanga me te whakaiti i te ātete rongoā. I tua atu, kua tūhuratia te cisplatin mō ōna tono i roto i te mara o te pūtaiao rauemi me te nanotechnology. Kua whakamahia i roto i te hanganga o ngā nanoparticles me ngā nanomaterials kei roto te platinum me ngā tono pea i roto i te tuku rongoā, te whakaahua, me te ine. Nā te kaha tauhohenga ahurei me te matū taunga o te cisplatin, he kaupapa whakamere tēnei mō te whakawhanake i ngā rauemi hou me ngā tono hangarau nano. Hei whakarāpopototanga, ko te diammineplatinum(II) nitrite, cisplatin rānei, he rongoā ārai matepukupuku e whakamahia whānuitia ana, ā, he tono pea ki te matū rongoā, te pūtaiao rauemi, me te hangarau nano. Nā tōna taiao taunga ahurei me te kaha tauhohenga ahurei, he kaupapa whakamere tēnei mō te whakawhanake i ngā kaihoko rongoā hou, ngā rauemi mahi, me ngā tono hangarau nano.