Candesartan CAS:139481-59-7 Kaihanga Kaiwhakarato

He kaitukino whiriwhiri a Candesartan mō te AT1 (angiotensin II receptor 1). Mā te aukati i ngā kaitukino angiotensin ka aukati i te vasoconstriction me te hanga o te aldosterone, ka heke te kukū wai me te konutai i roto i te toto toto. Ka whakaatuhia he pānga antihypertensive i roto i ngā tauira kararehe. Whakamahia hei rongoā mō te ngoikore o te ngākau, hei antihypertensive. Kāore a Candesartan e pā ki te oranga o te pūtau, te tipu rānei, engari ka whakanui ake i te whakaaturanga o te VEGF me te interleukin-8 i roto i te reo whakatipu o ngā pūtau KU-19-19. Ka taea e Candesartan (0.1 nM) te whakaiti i te urupare whakawhāiti mōrahi ki te angiotensin II mā te 50%.