Boc-Trp-OSu CAS:3392-11-8

He mea nui a Boc-Trp-OSu i roto i te matū honohono koiora, inā koa i roto i te mahi a ngā peptide me ngā pūmua mō ngā tono kua tohua. Hei pānga ester NHS, ka āwhina i te hononga honohono o te wāhanga tryptophan kua tiakina e Boc me ngā amine tuatahi kei roto i ngā waikawa amino, ngā peptide, ngā pūmua rānei. Mā tēnei hononga whiriwhiri ka taea te whakarerekē tika i ngā toenga waikawa amino motuhake i roto i te raupapa peptide, i te pito-N rānei o te pūmua, ka taea ai te whakauru i ngā rōpū mahi, ngā tapanga rānei mō ngā kaupapa rerekē. Ka whakamahia e ngā kairangahau me ngā tohunga koiora a Boc-Trp-OSu i roto i te whakawhanaketanga o ngā hononga peptide mō ngā tono pēnei i te tuku rongoā kua tohua, te whakamātautau ārai mate, me te mahi koiora. Mā te hono i ngā peptide kua whakarerekētia e Boc-Trp-OSu ki ngā ngota, ki ngā mata rānei kua tohua, ka taea e rātou te hanga i ngā hanganga koiora ka taea te taunekeneke whiriwhiri me ngā kaiwhakawhiwhi pūtau, ngā antigen, ngā matrices koiora rānei. Hei tāpiritanga, ka kitea te whakamahinga o Boc-Trp-OSu i roto i te whakarite i ngā hononga peptide-pūmua hei whakaputa i ngā hononga antibody-drug (ADC) me te tapanga pūmua mō ngā whakamātautau whakaahua me te tātaritanga. Nā te maha o ngā whakamahinga o Boc-Trp-OSu, he taputapu nui tēnei i roto i ngā mara kanorau pērā i te koiora matū, te hangarau koiora, me ngā pūtaiao rongoā. Ko tōna hototahi ki ngā kawa honohono koiora, te kaha tauhohenga teitei, me te whiriwhiri ka whai wāhi ki tōna whakamahinga whānui i roto i ngā taiao mātauranga me ngā taiao ahumahi. Ahakoa e whakamahia ana i roto i te rangahau taketake, i te whakawhanaketanga rānei o ngā rongoā matatau, ka taea e Boc-Trp-OSu te hanga i ngā hononga peptide kua whakaritea kia whai kiko ki te whakatairanga i ngā maimoatanga kua tohua me ngā tātaritanga ngota.