Amphotericin B – Te momo werohanga CAS:1397-89-3

Ka whakamahia te werohanga Amphotericin B hei rongoā i ngā mate harore nui pērā i te candidemia, te aspergillosis invasive, te meningitis cryptococcal, me te mucormycosis, inā koa i roto i ngā tūroro ngoikore te pūnaha ārai mate, i te hunga rānei he ngoikore te pūnaha ārai mate. Nā tōna kaha antifungal, ka kiia te werohanga amphotericin B hei rongoā tuatahi mō ngā mate harore nui. Ka tukuna e ngā tohunga hauora te amphotericin B mā roto i te uaua, me te aroturuki marie i ngā tūroro i te wā e werohanga ana hei whakahaere i ngā pānga kino pea, tae atu ki te kirika, te makariri, me ngā tauhohenga e pā ana ki te werohanga. Ko te horopeta me te roa o te rongoā amphotericin B ka whakaritea ki te mate harore motuhake, te āhua hauora o te tūroro, me tetahi ngoikoretanga o te okana. I te mea he paitini ki te roro me te kaha ki te whakararuraru i te electrolyte, he mea nui te aroturuki tata i te mahi tākihi me ngā taumata electrolyte i te wā e rongoā ana i te amphotericin B. Ka taea te whakamahi i ngā whakatakotoranga lipid o te amphotericin B hei whakaiti i te paitini tākihi me ngā tauhohenga e pā ana ki te werohanga e pā ana ki te amphotericin B deoxycholate tikanga. Mā te aroturuki tonu i ngā pānga kino, pērā i te ngoikore o te whatukuhu me te hypokalemia, me te tiaki tautoko tika, ka āwhina i te whakahaere i te haumaru me te manawanui o te rongoā amphotericin B. Ka āta paunatia e ngā kaiwhakarato hauora ngā painga o te maimoatanga me ngā mōrearea pea, me te whakarite kia whiwhi ngā tūroro i te rongoā harore tika me te whakaiti i te pānga o ngā pānga kino. Mā te arotahi tika ki ngā mate harore kino, he mea nui te werohanga amphotericin B ki te aro atu ki ngā āhuatanga morearea me te whakarato i ngā kōwhiringa rongoā mō ngā tūroro e pāngia ana e ngā mate harore uaua.