Waikawa 2-Amino-3-(4-hydroxyphenyl)propanoic CAS:556-03-6

Pānga ki te Mate a Parkinson: Ko te L-DOPA te rongoā tino whai hua mō te rongoā i te mate a Parkinson. Ko te mate a Parkinson ka puta mai i te korenga o te dopamine i roto i ngā wāhanga motuhake o te roro. Ko te L-DOPA he matūtake ki te dopamine, ā, ka taea e ia te whiti i te arai toto-roro hei whakanui ake i ngā taumata dopamine, ā, mā reira ka whakamama i ngā tohu nekehanga o te mate.

Te Whakamahinga i roto i te Maimoatanga o te Mate a Parkinson: He mea noa te whakamahi tahi i te L-DOPA me tētahi aukati decarboxylase ā-rohe (pērā i te carbidopa) hei whakarei ake i tōna whai huatanga. Ka ārai te aukati decarboxylase i te hurihanga o te L-DOPA ki te dopamine i roto i ngā kiko ā-rohe, ka taea ai te nui ake o te L-DOPA kia tae ki te roro.

Te Whakahaere i ngā Tohumate Nekeneke: Ka āwhina te L-DOPA ki te whakaiti i ngā tohumate nekeneke e pā ana ki te mate a Parkinson, tae atu ki te wiri, te pakari, te bradykinesia (te puhoi o te nekehanga), me te kore pumau o te tū. Ka whakapai ake i te mahi nekeneke, ā, ka taea e ngā tūroro te whakahoki mai i te mana whakahaere ki ā rātou nekehanga.

Ngā Pānga Taha: Ahakoa he whai hua te L-DOPA i te nuinga o te wā ki te whakahaere i ngā tohumate o Parkinson, ka taea hoki e ia te arahi ki ētahi pānga taha. Kei roto i ēnei ko ngā dyskinesias (ngā nekehanga koretake), ngā raruraru puku (pēnei i te whakapairuaki, te ruaki, me te mate puku), te toto toto iti, ngā moemoeā, me ngā huringa wairua. Ka rerekē te kaha o ngā pānga taha, ā, me āta aroturuki me te whakarerekē i te horopeta rongoā.

Ngā Mahi Rerekē: Haunga te rongoā i te mate a Parkinson, kua tūhuratia te L-DOPA mō ētahi atu mahi. Kua whakaatuhia tōna kaha ki te whakahaere i te mate waewae kore okioki, he mate e tohuhia ana e te hiahia ki te neke i ngā waewae, ka arahi ki te mamae me te uaua ki te moe. Tērā pea he pānga pai a te L-DOPA ki ētahi momo dystonia, he mate nekehanga pūnaha io.