1-β-D-Arabinofuranosyluracil CAS:3083-77-0

Ko te 1-β-D-Arabinofuranosyluracil, e mōhiotia ana ko te 1-β-D-Arabinofuranosylcytosine, ko te ara-C rānei, he rite ki te nucleoside e whakamahia ana hei rongoā chemotherapy hei rongoā i te mate pukupuku. He tino whai hua ki te mate leukemia me te lymphoma mā te aukati i te tipu me te horapa o ngā pūtau mate pukupuku i roto i te tinana.

Ko te tikanga mahi ko te whakaurunga o te ara-C ki roto i te DNA o ngā pūtau matepukupuku, ka whakararuraru i te tukanga hanga DNA, ā, ka mutu, ka mate ngā pūtau. He maha ngā wā ka whakamahia te Ara-C hei wāhanga o ngā tikanga whakakotahitanga o te chemotherapy, ā, ka taea te tuku mā te uaua.

Ko te whakamahinga o te 1-β-D-Arabinofuranosyluracil i roto i ngā tautuhinga haumanu he rongoā tuatahi mō ngā momo leukemia me te lymphoma.